Monday, February 2, 2015

Study group discussion: Cause of decreased glucose levels in CSF in bacterial meningitis

I have a question, my professor told us that the cause of decreased glucose in CSF relates to permeability changes caused by the exudates. Which I find a good reason for the protein levels but glucose is not the same. In books and other references, I found the reason being bacterial and brain tissue consumption of glucose and non replenishment of it being the cause.

Can someone tell me for sure the cause for glucose depletion in csf in meningitis?

I think it's the glucose consumption. Permeability changes play a minor role.

Yes I'd also go with consumption.

Because permeability changes occur in viral meningitis as well.

That's what I also thought because permeability changes occur in all of the forms even the non infective ones.

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