Friday, February 27, 2015

Study group discussion: Chagas disease

What comes to your mind when you hear of left ventricular apical aneurysm?

Two apical impulse.

Hint: Protozoa.

Chagas disease.

Brilliant!

Chagas disease causes destruction of the neural crest cells, right?
I know it causes Hirschprung disease. But how come apical aneurysm?

I think some parts of the heart are also formed from the neural crest cells.

The aorticopulmonary septum!

Chagas disease is associated with dilated cardiomyopathy.

I've heard of that.

Related fact: Chagas also causes achalasia.

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