What's Puetz jegher syndrome?
Hamartomatous polyp with pigmentation on lips.
Another life problem solved! Haha thanks!
Lkb1 is involved in PJS. How?
Peutz Jegher's Syndrome mnemonic:
Remember the initial letters of the disease - PJS.
P: Pigmented oral mucosa
J: Jejunal polyps
S: STK 11 defect
Thank you IkaN!
Oh nice. LKB1 kinase activity is lost due to somatic mutations. In Peutz Jegher's Syndrome, that is.