Sunday, May 24, 2015

Study group discussion: Leucine, tryptophan and niacin

Which essential amino acid interferes with the conversion of which another essential amino acid into niacin?

Leucine.

In shorghum or jowar, high leucine content inhibits conversion of tryptophan into niacin active form.

Any one knows the mechanism?

Because it inhibits quinolinate phopshoribosyl transferase.

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