I was trying to find out is hyperuricemia in Von Gierkes disease gender specific.. I didn't get the answer to my question (If you do, please let me know!), but I did found out that hyperuricemia, in general, is more common in men.
Estrogen in women helps the kidneys get rid of more uric acid, because it induces the expression of transporters called URAT1, OAT1 and OAT3.
Men have more muscle mass, more lactic acid production. Lactic acid competes with uric acid for excretion in the kidney.