Does Caffeine play a role in therapy of migraine? Or does it cause migraine?
Asking a doctor, he said yes caffeine heals pain in migraine attack. OK yea fine. But it can cause an attack too!! This is what I found something Amazing!
Migraine is a disorder characterised by acute pulsating headache, usually restricted to one side of head. Pulsatile dilatation of cranial blood vessels is the immediate cause of pain.
But we know headache is usually caused by vasoconstriction of cranial vessels and not vasodilation!
Actually, excess vasoconstriction or vasodilation, both cause less blood to reach brain parenchyma. This makes brain tissue cry for its necessary nutrients from blood!
In migraine there's excessive vasodilation of the vessels. So is the cause of acute pain. Caffeine constricts cranial blood vessels ( all other systemic vessels are dilated ). It is a CNS stimulant. (That's why we have more coffee at night while studying). :p
Now here comes the point. 1-2 cups of coffee (100-200mg) heal the pain by vasoconstriction. More than this will tend to decrease blood flow and so less supply to brain tissue.
That's why some people, who are in a habit of taking excess coffee or soft drinks, are more prone to headaches!
》 Caffeine is one of the constituents of medicines specific for treating migraine.
• MIGRIL: Ergotamine 2mg, Caffeine 100mg, cyclizine 50mg tab.
• VASOGRAIN: Ergotamine 1mg, Caffeine 100mg, Paracetamol 250mg, Prochlorperazine 2.5mg tab.
• CAFERGOT: Ergotamine 1mg tab. + Caffeine 100mg.
• Crocin Pain Relief: Paracetamol 650mg + Caffeine 50mg tab.
• Micropyrin: Aspirin 350mg tab. + Caffeine 20mg
PS: Remember, the moment you feel migraine symptoms, have coffee. It is the best and most effective way to heal pain, without significant side effects.