Tuesday, August 8, 2017

Composition of Bone cement

Hello :)

Today I saw a case of Infected AMP implant. Following questions were asked to me regarding bone cement.
Q. Composition of bone cement.

A. Bone cement consist of :- Powder and liquid.

POWDER
1. Polymer : Polymethylmethacrylate (PMMA)
2. Initiator : Benzoyl peroxide (BPO)
3. Radio-opacifier : Barium sulphate , Zirconia
4. Antibiotic :- Gentamicin (commonly)

LIQUID
1. Monomer : Methylmethacrylate (MMA)
2. Accelerator : N,N Dimethy Paratoluidine (DMPT)
3. Stabilizer : Hydroquinone

Q.Antibiotics used as additives for PMMA bone cement.
A. Antibiotics commonly used as additives for PMMA bone cement include:
- vancomycin, (MRSA)
-gentamicin,
-meropenem,
-in addition totobramycin.

Also, successful non-antibiotic bactericides that have been used as bone cement additives include:-
- Quaternary ammonium compounds (benzalconium chloride and cetylpyridinium chloride)

That's all for today.
-Upasana Y. :)

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