Showing posts with label Biostatistics. Show all posts
Showing posts with label Biostatistics. Show all posts

Wednesday, June 17, 2020

Topics to read before PG entrance exams!

Hello Awesomites!

The aim is to help the students who want to give upcoming NEET PG Exam and are clueless about how to plan and prepare ?
I know my friend struggling day in and out for life in Covid wards. Exams doesn't matter now.
When they will have time in hand I want to help them out with plan beforehand. They are already brilliant enough to have been through all the challenges. :)

I know you can't predict what is important for this or next exams. Atleast with time in hand you can glance through some topics that contribute 70% of any exam. I am sharing the list 1st year subject I made during my preparation.

1.ANATOMY
  • Embryology 
  1. Pharyngeal arches
  2. Neural crest derivatives
  3. Oogenesis and spermatogenesis
  4. Notochord and remnants 
  5. Extraembryonic mesoderm
  6. Diaphragm 
  7. Cardiovascular system ( Abnormal subclavian artery)
  8. Urogenital system 
  • Histology 
  1. Cerebellum
  2. Osteoblasts
  3. Urinary bladder epithelium
  4. Cell junctions
  5. Collagen types
  6. cartilage
  7. Tonsil,Lymph nodes, spleen,thymus
  8. Stomach glands
  9. Skin with sebaceous glands
  10. Connective tissue types
  11. Retina 
  12. Salivary gland
  • NEUROLOGY
  1. Fornix 
  2. Corpus callosum
  3. Cranial nerves and its lesion
  4. Brainstem syndromes (lateral medullary )
  5. Foramen of skull
  6. Facial nerve and trigeminal nerve
  7. blood brain barrier
  8. Functional area and functional columns
  9. Parasympathetic ganglion 
  10. Phrenic nerve and vagus
  • GROSS
  1.  Compartments of lower limb with nerve and blood supply
  2. Blood supply of thyroid,oesophagus,ureter,Anal canal 
  3. Waldeyer ring
  4. External carotid artery
  5. Circle of willis
  6. Muscle of eye
  7. Brachial plexus (Sensory and motor supply of upper limb)
  8. Perineum
  9. Cruciate ligaments
  10. Vocal cords
  11. Mediastinum
  12. IVC tributaries
  13. Cavernous sinus and superior orbital fissure 
  14. Splanchanic plexus
2. BIOCHEMISTRY
  • Inborn error of metabolism (Types,Enzyme deficient,hallmark feature,Investigation of choice and treatment)
  • Rate limiting step 
  • Carbohydrate metabolism (Glycolysis,Glycogen storage disease,Glucogenesis,glycogenolysis,PFK-1)
  • Lipid metabolism ( Hyperlipoproteinemia and hypolipoproteinemia)
  • Vitamin (Coenzyme)
  • Electron transport chain inhibitor
  • Heme metabolism and Porphyria
  • Ketone body formation 
  • Urea cycle disorder
  • Competitive, non competitive and allosteric inhibitors
  • Mitochondrial disorders 
  • Amino acid disorder
  • Lead poisoning
  • Translation process 
3.PHYSIOLOGY
  • Receptors
  • Neurotransmitter and functions
  • Second messenger
  • Reflexes
  • Baroreceptors and chemorecptors
  • JVP 
  • ECG And EEG
  • Spirometry
  • RAAS 
  • Counter current exchanger and multiplier
  • Factors affecting compliance of lung 
  • Action potential
  • Smooth muscle and cardiac muscle
  • Channels and types 
  • GIT hormones 
  • Tracts and lesions(brown sequerd syndrome)
  • LH,FSH,GH and insulin glucagon
 Following are the list of 2nd year topics.

1.FORENSIC MEDICINE
  • Ballistics (Bullet ranges)
  • Identification (female male, blood sample)
  • Recent amendments in acts (POCSO act, MTP Act)
  • Application of IPC,CrPC sections
  • Postmortem changes
  • Dentition And Xray of wrist elbow and pelvis to determine age
  • Injuries -fracture of skull, RTA, Bruise
  • Toxicology- Plant based image, Preservation of viscera, Snakes,Arsenic, OP poisoning,Mercury,cadmium,Cardiac poison
  • Consent
  • Grievous hurt and murder vs culpable homicide
  • Seminal stains
  • Dowry death and Rape
  • Battered baby syndrome
  • Plant Toxicology (castor,abrus,strychnine,Dhatura,Aconite,Oleander,Calotropis,Opium,Cannabis)
2. PATHOLOGY-
  • Breast cancer, Lung cancer and Ovarian and testicular cancer
  • CD markers
  • Hemolytic anemia
  • Vasculitis
  • Endocarditis And MI
  • Types of hypersensitivity reaction
  • Platelet and coagulation disorder(ITP,TTP,hemophilias,vWD)
  • Stains And vacutainers
  • Transfusion reaction 
  • Graft rejction
  • Crohns vs Ulcerative colitis
  • Necrosis, apoptosis and its variant
  • Mode of inheritance
  • Leukemia and lymphoma prognostic markers
  • Renal histology and gross
  • Liver histology and gross
  • CNS tumors 
3.PHARMACOLOGY
  • Antimicrobial Drug of choice and mechanism of action 
  • Classification - aminoglycoside , MRSA And drugs for cystic fibrosis
  • Hypolipidemic Agents 
  • Asthma ( New drugs and guidelines)
  • Arthritis (RA and gout)
  • General pharmacology ( Pharmacokinetics,clinical trial,Pharmacodynamics)
  • Concentration dependent kinetics and time dependent kinetics and post antibiotic effect
  • Anti TB drugs
  • Anti viral and anti HIV (anti hep B and C)
  • Anti fungal
  • CVS- MI ,HF, angina managment
  • Endocrine- DM,Osteoporosis,SERM,SERD,Gnrh agonist
  • GIT-Constipation (opioid induced,IBS related) ,Diarrhea,peptic ulcer
  • CNS-Anti epileptic, Sedative,lithium toxicity,neurodegenerative disorder, side effect 
  • ANS- Emergency medicines,anaphylaxis, receptors ,poisoning 
  • Chemotherapy-Anticancer,monoclonal antibody,small molecules,kinase inhibitors
  • Prostaglandins 
  • Insulin 
4.MICROBIOLOGY-
  • Sterilisation and disinfection (Indicator)
  • Immunology (Antibody,complement deficiency,Primary immunodeficiency)
  • Latest outbreaks (Zika,Congohemorrhagic fever,Ebola,Corona)
  • Sexually transmitted infections
  • Vectors
  • Parasitology -Eggs
  • Congenital infections-Toxoplasmosis,congenital syphillis,rubella,herpes,varicella
  • HPV infection,HHV-8
  • Bioterrorism
  • Larva migrans,larva currens (cutaneous and visceral)
  • CD4 counts and Opportunistic infection
  •  HIV and TB
  • Food poisoning
  • Atypical bacteria treatment and infection 
  • Dimorphic fungi
  • Actinomycosis,Botryomycosis and eumycetoma
  • Meningitis
  • Exanthematous disease
  • Neisseria,diphtheria,Listeria,bacillus anthrax,legionella,campylobacter jejuni
  • Bacterial virulence factors,growth factors
  • Rickettsial disease, spirochetes(weils ds) 
  • Drug resistance mechanism

Following is the list of 3rd year topics.

1.COMMUNITY MEDICINE-
  • Surveillance programs
  • Sensitivity, specificity,PPV and NPV (Screening of disease)
  • Types of studies 
  • Odds ratio and relative risk ratio
  • Bias
  • Sampling 
  • Biostatistics- central tendency  (Box and whisker plot )
  •  Level of prevention 
  • Vaccine and types (Toxoid and live attenuated)
  • Demography and family planning
  • Biomedical waste
  • Health programmes ( RNTCP, HIV)
  • Communication
  • Nutrition and related programmes
  • Disaster
  • Null hypothesis,P value and alpha value
  • Confidence limit 
2.OPHTHALMOLOGY-
  •  Refractive errors (Astigmatism)
  • Surgery and post op complication(Glaucoma,cataract,squint)
  • Conjuctivitis
  • Corneal ulcer (Bacterial,fungal and herpetic) (Stains)
  • ROP and systemic retinopathy (Hypertensive and diabetic retinopathy)
  • Retinitis pigmentosa and syndromes
  • Retinal detachment and cause
  • Retinoblastoma
  •  Strabismus
  • Optic neuritis
  • Visual field defect 
  • Blow out fracture and trauma to eye
  • Glaucoma and drugs(Contraindication and indication)
  • Managment of ptosis
  • Light reflex and accomodation reflex and pupil
  • 3,4,6 Cranial nerve
  •  OCT ,Fluorescein angiograhy,tonometers,charts,
  • Sudden loss of vision and gradual loss of vision differentials
3. ENT-
  • Appearance of tympanic membrane in various disease
  • Surgery (Tonsillectomy,Adenoidectomy,Mastoidectomy)
  • Paranasal sinus
  • CSF rhinorrhea
  • Laryngeal disease (Papilloma,vocal cord paralysis, laryngeal muscles action, laryngeal cancers)
  • Tracheostomy
  • Abscess 
  • Nasopharyngeal carcinoma
  • Juvenile angiofibroma
  • Test of hearing and vertigo
  • Otosclerosis
  • Cochlear implants
  • Oral cavity cancers 
  • cervical Lymph node  and neck dissections
 Following is the list of Final year topics.

 1.OBSTETRIC AND GYNECOLOGY-

  • Pre-eclampsia (Definitions)
  • HELLP
  • PPH (prophylaxis and treatment)
  • Perineal tear (Types and managment)
  • Diabetes and anomalies scan 
  • Shoulder dystocia maneuvers
  • Molar pregnancy (High risk and low risk for GTN)
  • Ectopic (Diagnosis, Investigation and managment)
  • Abortions 
  • Recurrent pregnancy loss (Investigations and causes)
  • Cervical incompetence
  • MTP
  • Diagnosis and physiological changes of pregnancy 
  •  Abruptio vs placenta previa vs Vasa previa
  • Heart disease
  • MgSO4 and drug
  • Fetal monitoring -NST,BPP,doppler
  • Twins and complications
  • Labor-stages,partogram
  • Placenta types and associated pathology
  • Rh incompatibility
  • Amenorrhea (primary and secondary)
  • Mullerian anomalies (Class)
  • Asherman, AIS,Gonadectomy indication
  • Puberty and precocious puberty
  • Menopause (Hormone replacement therapy guidelines) 
  • Postmenopausal bleeding and premature ovarian failure (Levels of FSH)
  • Semen analysis (Evaluation and IUI and TESE)
  • PCOS -Diagnosis,drugs
  • Endometriosis
  • Cervical,vulval,ovarian,endometrial cancer,Fibroid
  • Krukenberg
  • PID
  • Prolapse 
  • Emergency contaceptives
  • IUD
  • Absolute contraindications in whole subject
  • Female sterilisation  
2.PEDIATRICS-
  • Developmental milestones
  • Neonatal reflexes
  • Neonatal resuscitation
  • Jaudice,sepsis,Hyaline membrane disease
  • Congenital infections-TORCH
  • Vaccines(IAP and NIS)
  • Diarrhea,pneumonia,dehydration managment
  • Pediatric epilepsy
  • Febrile seizure (Risk factors,recurrent risk,prohylaxis)
  • Severe acute malnutrition
  • Rickets
  • meningitis
  • Neuro-Cerebral palsy and neurocutaneous syndrome
  • Pediatric vasculitis-HSP and Kawasaki Disease
  •  Nephrotic syndrome
  • Congenital heart disease( VSD,TOF,TGA and ductus dependent CHD)
  • Trisomies
  • Hypoxic Ischemic encephalopathy VS Periventricular leukomalacia
  • Fluid managment including shock managment in children
  • Childhood pneumonia, Epiglottitis, Acute laryngotracheobronchitis
  • Microcephaly and macrocephaly 
  • Hydrocephalus and Neural tube defect  
  • Fetal alcohol syndrome,warfarin syndrome
3. ANESTHESIA-
  • IV anesthetic agents (Propofol)
  • Day care surgery (Drug of choice)
  • Venous air embolism
  • Local anesthetic (Remember concentration also)
  • Vaporisers color 
  • Inhalational agents 
  • Monitoring (Capnography)
  • Color coding of cylinder
  • Circuits
  • Mallampati and ASA grading
  • Premedication duration of stoppage and continuation
  • Muscle relaxant
  • Airway devices
  • Endotracheal tube (formula)
  • Epidural vs spinal anesthesia (Level of blocks)
  • Modes of ventilation
 4.DERMATOLOGY-
  •  Pigmentation Diseases 
  1. Hyperpigmentation
  2. Nevus (Nevus of ota/mongolian spot/CMN/AMN)
  3. Melasma
  4. Acanthosis nigricans
  5. Becker nevus
  6. Hypopigmentation -PKDL/Pityriasis versicolor/alba/Hansens
  7. Depigmentation-Vitiligo/Contact leukoderma
  • Signs (Auspitz,nikolsky,bulla spread sign)
  • Histopathology of psoriasis and lichen planus
  • Mast cell disorder-Urticaria pigmentosa image
  • Papulosquamous disease - Psoriasis ,lichen planus
  • Treatment of Psoriasis
  • STD (Syphillis,chancroid,donovanosis,Herpes genitalis,syndromic approach)
  • Microbiology of STD organism( Dark ground,school of fish,Tzanck smear,Donovan body,Gonococcus)
  • Drug Reaction -Fixed drug eruption, erythema multiforme,SJS/TEN
  •  Blistering disease 
  1. Pemphigus(clinical treatment)
  2. Bullos pemphigoid
  3. dermatitis herpetiformis
  4. Histopathology of blister level and Direct immunofluorescence image
  • Infections
  1. Fungal (Tinea /pityriasis versicolor)
  2. Hansens 
  3. TB
  4. Viral (HPV/HHV/Molluscum contagiosum)
  • Hair disease-Alopecia images,DLE,trichotillomania
  • Acne,Rosacea
  • cutaneous markers of internal malignancy
5.RADIOLOGY-
  • Emergency radiology-RTA,splenic injury,FAST,Perforation
  • Radiological anatomy especially applied aspect
  • CNS tumor
  • Bone tumor
  • BIRADS
  • TIRADS
  • Radiation physics and acute radiation syndrome
  • Radiotherapy basics
  • Contrast in various studies
  • USG and doppler
  • Doppler waveforms
6.ORTHOPEDICS-
  • Knee joint (Everything)
  • Shoulder dislocation
  • Bone (Oncology+radiological picture)
  • Pediatric Hip(Rdaiology +managment)
  • Infections(TB,Osteomyelitis)
  • CTEV
  • AVN
  • Tennis elbow and dequeverian
  • Eponyms and test
  • Blood supply of femur
  • Pseudoarthrosis
  • Genu varum/valgus,cubitus varus/valgus
  • malunion 
  • Instruments
7.SURGERY-
  • Glasgow coma scale (Changes)
  • Burn
  • Cannula color coding 
  • Triage
  • Trauma
  • Incisions,suture,foleys,NG tube,Knots,Scores
  • Latest updates in breast cancer,thyroid and hepatobiliary cancers,Pancreatic cancer,stomach,colorectal cancer
  • Bed sores staging 
  •  Renal stones managment
  • Gall stone managment and surgical complication
  • Bariatric surgery
  • Acute pancreatitis managment 
  • Upper GI and lower GI bleed management and causes
  • Aortic aneurysm
  • Meckel diverticulum
  • Wound classification
  • Cancer-(Breast,rectum,stomach,oesophagus,HCC,prostate,thyroid)
  • Cancer follow up duration 
  • Carcinoid and GIST and gastrinoma
 8.MEDICINE-
  •  ECG visuals
  • Cardiac emergencies-Arrest,Unstable angina,MI,Arrhythmia,Dissection
  • Respiratory emergency-Pulmonary embolism,pneumothorax,Asthma 
  • Stroke
  • Meningitis (Bacterial,viral,aseptic)
  • Approach to patient in Coma
  • Seizure
  • Electrolyte imbalance
  • ABG
  • Hypertension and its emergency and management
  • Murmurs and valvular lesions
  • Pericardial d/o
  • hepatitis(Viral,autoimmune)
  • Non alcoholic and alcoholic liver disease
  • Glomerular disease
  • UTI
  • CKD
  • DM (management of different complications)
  • Neurodegenerative d/o ,neuropathy,myopathy
  • Septic shock guidelines
  • GBS
  • Poisoning 
  • New asthma guidelines
  • RTA and Inherited channelopathies
  • MEN syndrome
  • SIADH, DI,Pheochromocytoma
  • AIDS defining illness
  • Connective tissue disorder
  • Infective endocarditis and rheumatic heart disease
  • Prakinson and alzheimers
  • IBS,UC ,Crohns
  • Cardiomyopathy
  • Jones and dukes criteria
  • dyslipidemia management 
10.PSYCHIATRY-
  • General psychiatry (terms and its meaning )
  • MMSE
  • Psychotic disorders
  1. Schizophrenia
  2. Delusional d/o- Named syndromes (Capgras,Fregoli,Othello,Ekbom)
  • Mood disorder (Treatment is very important)
  1. Mania
  2. Depression
  3. Bipolar
  • Neurotic disorder 
  1. Anxiety disorder
  2. OCD related disorder
  3. Dissociative disorder
  4. Trauma and stress related disorder
  5. Somatoform disorder
  • Substance abuse and deaddiction
  • Organic mental disorder(dementia)
  • Sleep disorder
  • Eating disorder
  • Sexual disorder
  • Personality types and disorder
  • Drugs (SSRI and its sideeffect)
  • Psychotherapy types and choice
  • Defence mechanism  
You can edit this according to you. 
Hope it will help.
-Upasana Y.

Friday, April 24, 2020

Funnel Plot

-also called as Begg’s plot
-type of scatter plot
-used to examine biases in meta-analyses

An ideal funnel plot is symmetric.
If no biases, 95% of studies lie within the triangle.


Wednesday, April 1, 2020

COVID-19: Lessons from coronavirus outbreak in China and formulating a strategy

Hello awesomites!

The following information is regarding the situation of COVID19 in China and how did China manage to reduce the incidence of new cases.


Image by  Nakeya. Medicowesome 2020

Thursday, April 11, 2019

Hierarchy Of Evidence

Evidence-based medicine is the conscientious and judicious use of current, best research evidence to optimise management plans.
Here’s the order of importance.


[Please click on the image to enhance it]



That’d be all.


- Ashish Singh


Reference(s):
1. Evidence based medicine: what it is and what it isn't by Sackett et al, 1996.








Thursday, December 7, 2017

Likelihood ratio mnemonic

Hello! :)

The likelihood ratio of a positive test result (LR+) is sensitivity divided by 1- specificity.

The likelihood ratio of a negative test result (LR-) is 1- sensitivity divided by specificity.

How I remember the formulae for LR+ and LR-

Sunday, September 24, 2017

Relation between Type I, Type II errors and Null hypothesis (mnemonic)

Biostatistics can really be dry and hard to engulf sometimes. 

One of the things that always confused me was when to accept and when to reject the null hypothesis. 

Since  mnemonics are one of the best things ever, here you go:

Type ONE error:
You use a verb with ONE consonant => reJect => so you reJect Null hypothesis

Type TWO error:
You use a verb with TWO consonants => aCCept => so you aCCept Null hypothesis

& that's it! :)

-Murad

Sunday, April 23, 2017

Number needed to treat and number needed to harm mnemonic

Hello!

Number needed to treat = 1 / Absolute risk reduction

Mnemonic: TARR - Treat Absolute Risk Reduction

Number needed to harm = 1 / Attributable risk

Mnemonic: HARM - Harm Attributable Risk M

That's all
-IkaN

Friday, April 14, 2017

Case control study vs Cohort study mnemonic

Super short post :)

Case control study - Start with an outcome and go back in time to study the risk factor.
Simplified: Case (Diseased) vs Control (No disease)

Cohort study - Start with risk factor and see who developed the disease and who did not.
Mnemonic: cOhOrt has two O's.
One O has an R (cohORt), which means one group has the risk factor.
Other O does not have an R (cOhort), which means the other group does not have the risk factor.
Compare the two to see who gets the disease.

How to remember that case control studies measure odds ratio and cohort studies measure relative risk:

You take surgical "cases" to the "OR" (Operating room)
Case control study - Odds Ratio

cohoRRRRRRt measures Relative Risk.

kthxbye!

-IkaN

Thursday, December 8, 2016

Descriptive Epidemiology

Hello everyone !
Here's a video telling you a little bit of the Descriptive Epidemiology.
Let me know how you like it and I can continue to make some more to finish it up and tell you more about Epidemics!

Thursday, October 29, 2015

Validity and reliability mnemonic

Hey everyone!

Someone requested me to make a mnemonic on reliability and validity. Let me tell you in short what these terms mean!

What is validity and reliability?

Let's take the example of measuring blood glucose levels.
Suppose, we have developed a test to measure glucose levels and we measure it in healthy man. Normal standard we have set is, let's say, 80.

Reliability means test will give the same value each time. Let's say, we measured three times it gave reading of 120, 120, 120 that is reliable. Reliability is consistency. Also called precision.

But validity means the test will give a value which is close to our standard value, that is, 80 in this case. The three readings we get this time are 82, 85, 79. So this test is reliable, but not valid. Validity is also called accuracy. Validity is not affected by sample size.

This interplay of words messes up with one of my readers brain, so I'm sharing the mnemonic I made on it. I thought it was silly at first, to use a mnemonic to remember words, but I'm glad you all are as weird as me.

VACuum = Validity + ACcuracy

PReCiSe = Precision + Reliability + Consistency + Sample size dependent

That's all!

Life is so good. I've never been so happy and calm. I'll tell you why soon, but for now, I just wanted you guys to know (:

-IkaN

Related post: Biostatistics mnemonic

Monday, February 2, 2015

Sunday, February 23, 2014

Berksonian bias, Pygmalion effect and Hawthorne effect mnemonic

Hey everyone!
Because the names are so hard to remember, I make silly associations out of them and I hope it helps you all too =)

Berksonian bias: Selection bias that arises from evaluating data on biased patients and hospital records only.

When it comes to Berksonian bias I think of Preston Berke from Grey's anatomy and I know that it's associated with the hospital and patients!

Pygmalion effect: The observer-expectancy effect is a form of reactivity in which a researcher's cognitive bias causes them to unconsciously influence the participants of an experiment.

Researchers are pigs. They think their research is always right. Pygmalion effect! xD

Hawthorne effect: When behavior of the subjects of the study change because they know they're being observed.

Haww I am being studied. Hawthorne effect!

That's all!

Pray that I do well in my exams.

-IkaN

This is awesome. A Tumblr post with gifs and tables. Yaay!

Saturday, December 28, 2013

Bio-statistics mnemonics, tips & tricks

Hey everyone!

I thought of writing the whole blog at once as I have a lot of mnemonics and tricks but I barely get time and it has been pending for a long time now so I thought of publishing it, hoping I'll keep updating this post as and when possible :)

Relative risk and Attributable risk mnemonic