Saturday, June 27, 2020

Post BCG injection site reaction

Hello Awesomites!


Today,the mother came with one week 5 day old newborn. She noticed a papule in left upper arm of newborn. She was afraid and thus visited the OPD.On history, the child was vaccinated on day 0 . So we counselled her as it was Post-BCG Vaccination injection site reaction characterized by a papule, which may be red, tender and indurated. The papule commences two or more weeks after vaccination and then may progress to become ulcerated healing after 2-5 months leaving a superficial scar.


I forgot to take picture due to rush. You can google the pictures.

-Upasana Y. 

Monday, June 22, 2020

Rett syndrome notes

Hello friends!

Today we are going to learn about Rett syndrome

*Frequency : 1 in 15,000.
*90% of the cases are SPORADIC
*5-10% are X-Linked Dominant, so more common in females
(Remember males get only one X chromosome from mother whereas females get X chromosome each from mother and father).

*Mutation in gene : MeCP2.
*Virtually always seen in girls because males usually die in utero or shortly after birth.
*Important finding : Decreased pontine NE and Nigro-striatal Dopamine levels.

Clinical features
*At birth : Normal growth and normal head circumference.
*Normal attainment of milestones till 5-6 months of age, later there will be progressive regression of language (both receptive and expressive) and motor milestones.
*It causes Acquired Microcephaly.
*Hallmark : Repetitive hand writing movements with loss of purposeful movements.
*It can cause 5 As:
Apnea (intermittent)
Ataxia
Autistic behaviour
Arrhythmias
Acquired Microcephaly

*In addition to all of these, cyanosis, GTCS can also be seen.

*Staging :
Stage 1 : Onset stage (6-18 months)
Stage 2 : Rapid destructive (1-4 years) - 
Stage 3 : Plateau phase (2-10 years)
Stage 4 : Late motor phase (decreased motor movts) - Scoliosis can occur.

*Imaging : No pathognomonic finding. However, significant reduction on brain weight upto 60-80% is often seen.

*HPE : Decreased synapses, dendritic length and branching.

*Treatment : Supportive.

Hope it will help :)

Madhuri.









Sunday, June 21, 2020

Pediatric Residency Series: Conferences

The Table below has the name of some Pediatric conferences and the respective subspecialty                          


Pediatric Conferences 

Subspecialty 

Conference 

Dates 

Link 

Everything / all subspecialties 

Pediatric Academic Societies (PAS) 

April/May 

https://2020.pas-meeting.org/ 

 

Southern Society of Pediatric Research (SSPR) 
(Mainly for Southern states) 

February 

https://www.southernspr.org/l/default.asp 

Pediatric Cardiology 

American Heart Association conference(AHA) 

November 

https://professional.heart.org/professional/EducationMeetings/MeetingsLiveCME/ScientificSessions/UCM_316900_Scientific-Sessions.jsp 

 

American College of Cardiology conference(ACC) 

March 

https://accscientificsession.acc.org/ 

 

CHOP: Annual Update on Pediatric and Congenital Cardiovascular Disease 

February 

https://chop.cloud-cme.com/default.aspx?P=5&EID=928 

Pediatric Allergy/Immunology 

American Academy of Allergy, Asthma, and Immunology (AAAAI) 

March 

http://aaaai2020.org/ 

 

American College of Allergy, Asthma, and Immunology (ACAAI)  

November 

https://annualmeeting.acaai.org/ 

 

Texas Allergy, Asthma, and Immunology Society (TAAIS) -no poster presentations  

April 

https://taais.org/intro-view/2020-taais-annual-meeting/ 

Pediatric Neurology 

Child Neurology Society (Getting a poster in may be difficult) 

October 

 

American Academy of Neurology  

April/May 

Child Abuse 

Ray E. Helfer Society. 

April 

Pediatric Genetics 

American Society of Human Genetics (ASHG) annual meeting 

October 

https://www.ashg.org/2019meeting/ 

 

Annual Clinical Genetics Meeting (ACGM) 

March 

https://www.acmgmeeting.net/acmg2020/Public/mainhall.aspx 

 

Society For Inherited Metabolic disorders (SIMD) 

March/April 

https://www.simd.org/meetings/ 

Pediatric Hematology/Oncology 

American Society of Pediatric Hemato-Oncology (ASPHO) 

May 

http://aspho.org/meetings/conference/overview 

 

American Society of Clinical Oncology (ASCO) 

Variable 

https://www.asco.org/meetings 

 

American Society of Hematology  

February 

https://icaho.binayfoundation.org/ash-review-2020/?gclid=Cj0KCQiAxfzvBRCZARIsAGA7YMygEl2NN94_002yg6RkPits6AjbbfMLdhbPSAHzHvMaE1xyc7rOtc4aAs5fEALw_wcB 

Pediatric Hospitalist Medicine 

Pediatric Hospitalist Medicine Conference 

July 

 


Will be updated as soon as more info become available :)

Do not forget to leave comments about names of conferences you know for different subspecilaties so they can be added to the table. 


-Murad