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Thursday, February 28, 2019
Cogan's Syndrome
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●Cogan's syndrome (CS) is a chronic inflammatory disorder that most commonly affects young adults. Clinical hallmarks are interstitial k...
Wednesday, February 27, 2019
GPA vs MPA Flares
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The distinction between GPA ( Granulomatosis with Polyangiitis) and MPA (Microscopic Polyangiitis) is important chiefly because of different...
ANCA titers and Disease flare.
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Does a rise in ANCA titers predict a disease flare? — This has been a controversial area in the literature almost since ANCA were first iden...
POTS Syndrome
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●The postural tachycardia syndrome (POTS) is defined as a form of orthostatic intolerance characterized by an excessive increase in heart ra...
Tuesday, February 26, 2019
Classification of Cryoglobulinemia
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●The Brouet classification criteria is the most commonly used system that classifies cryoglobulinemia into three different subgroups based o...
Eye Findings in GCA
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●Anterior ischemic optic neuropathy – At least 80 percent of cases of vision loss in patients with GCA are caused by AION . The ischemic ins...
Imaging Findings in PMR
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Imaging — As discussed above, there are characteristic features of periarticular structures (eg, bursitis and tenosynovitis) that can be se...
How to Diagnose Polymyalgia Rheumatica?
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General approach — There is no pathognomonic test or established diagnostic criteria for polymyalgia rheumatica (PMR). We use the presence o...
Adalimumab (Humira)
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Use Ankylosing spondylitis: Treatment (to reduce signs/symptoms) of active ankylosing spondylitis in adults Crohn disease: Treatment (to r...
Monday, February 25, 2019
Detection of Cryoglobulins
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Detection of cryoglobulins — To detect cryoglobulin, 10 to 20 mL of blood are drawn into syringes and/or collection tubes that have been pre...
Vision Loss in Giant Cell Arteritis
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Causes of vision loss — Permanent loss of vision in GCA results from arteritic anterior ischemic optic neuropathy (AION), central or branch...
Low Alkaline Phosphatase
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Subnormal values — Extremely low serum alkaline phosphatase concentrations can be seen in patients with fulminant Wilson disease complicated...
Sunday, February 24, 2019
Old Classification Criteria for Fibromyalgia
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The final 1990 ACR FM classification criteria included: ●Symptoms of widespread pain, occurring both above and below the waist and affectin...
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