#Microbiology
#PSM
2) SAR is 90%
3) Superficial rash
4) Single stage of rash
Here's a short mnemonic post for you!
Transcription is the process by which the DNA is converted into an RNA transcript ( Literally - the DNA is transcribed or written out as an RNA sequence).
The key enzyme needed for this process is RNA Polymerase.
In Eukaryotes , there are 3 different RNA Polymerases subtypes depending on which RNA they help code for.
We know that Ribo Nucleic Acids or RNA can be mRNA - Messenger RNA , tRNA or Transfer RNA , rRNA - Ribsomal RNA or one of the small nuclear RNAs - micro RNA - miRNA / siRNA.
Here's a mnemonic to memorize which RNA Polymerase codes for which of these -
Mnemonic - R MIS T5 (Read as R Mistify)
RNA Polymerase I = rRNA
RNA Polymerase II = mRNA, miRNAs , siRNAs
RNA Polymerase III = tRNA , 5S rRNA
This form of RNA specificity is not found on the Prokaryotes - and they have just one RNA Polymerase that bears it all , for all types of RNA !
This has been a quick summary of transcription and a helpful mnemonic for you!
Hope was helpful.
Stay awesome !
Happy Studying!
~ A.P.Burkholderia
#Medicowesome
#Ophthalmology
Q) In Dengue, all are seen w.r.t eye except:-
1) Cataract
2) Optic neuritis
3) Vitreous hemorrhage
4) Maculopathy
So, you basically cannot solve above problem if you don't know which portion dengue affects in eye.
Dengue affects posterior portion of the eye. So accordingly answer is
Cataract-Option 1
Some basics to cover over here.
Eyeball is divided into two segments or portion.
Anterior segment: Cornea to lens.
Volume - 0.31mL of Aqueous humor.
Posterior segment: Lens to retina.
Volume - 4mL of Vitreous humor.
Anterior segment is divided into two parts:-
Anterior chamber: Cornea to iris.
Volume- 0.25mL of Aqueous humor
Posterior chamber: Iris to lens.
Volume- 0.06mL of Aqueous humor
-Demotional bloke.
Question:
In Diabetic 3rd nerve palsy all are seen except
A) Pupil dilation
B) Outward and downward gaze
C) Ptosis
D) Impaired pupillary reflex
Let us start with the basic.
Mnemonic for extraocular muscles nerve supply
LR6 SO4 Rest3
Lateral rectus is supplied by 6th nerve or abducence nerve and superior oblique by 4th nerve or trochlear nerve and rest all muscles including LPS are supplied by 3rd muscle or occulomotor nerve.
In pupillary reflex,
Afferent nerve: Optic nerve
Efferent nerve: Occulomotor nerve.
So in case of 3rd nerve palsy, we will have less or no actions of all EOM except lateral rectus and superior oblique.
So we will have downward gaze (due to superior oblique) and outward gaze (due to lateral rectus) and Ptosis (because LPS is supplied by 3rd nerve! ).
Pupillary reflex is also disturbed so option 4 is also ruled out.
Here is a trick in this question. In DM and HTN, microangiopathy is seen due to which central fibers are affected.
Central part do not contribute to pupillary reflex.
This leads to no pupil dilation. In case of surgical conditions and trauma, peripheral fibers are affected which causes impaired pupillary reflex or pupil dilation.
-Demotional bloke.
Hello Everyone,
It's been really long since the last post! Well it's been hectic all the way to and through residency.
I was recently researching on the topic of antibiotics while I stumbled upon this excellent piece of information cum approach by Dr.Strong on starting Anbiotics.
Well everyone should ask themselves these 12 questions before starting any antibiotic for one's patient and trust me you'll end up choosing the most appropriate one.
This is how we don't contribute to the Antibuse- "Antibiotic Abuse"( my personal neologism)
So now coming back to the questions, ask yourself these questions before you start any antibiotics,
1) What condition is being treated?
2) What are the commonly known bacterial species causing that condition?
3) Which antibiotic group is typically active against those?
4) What are the local resistance patterns for the chose antibiotic?
5)Will there be adequate organ penetration?
6) What is the preferred route of administration?
7)Any specific contraindication of the antibiotic to look out for?
8) Any required dose adjustment for coexisting renal or hepatic diseases?
9) Any specific drug interactions to be considered?
10) When on therapy anything that needs periodic monitoring?
11) How can the therapy be narrowed once bacterial sensitivities are available?
12) What will be the anticipated duration of the therapy?
Let's take a step towards stopping the rampant Antibuse.
That's all for now.
Let's learn Together!
-Medha Vyas.