It is not necessary to remember these for most exams, but knowing them gives us a sense of completeness and makes us feel confident. Important for exams or not, I hope this post helps you! :)
As you go from M0 to M7, the cell is getting more and more differentiated.
WBCs, RBCs and Platelets is the order (wrap!)
I call promyelocytic leukemia with it's nick name, Pro! :D
Pro has 3 alphabets and so it's M3.
Other 3 letter words you should be familiar with PRO are DIC and VIT.
Acute promyelocytic leukemia is associated with disseminated intravascular coagulation (DIC).
All trans retinoic acid (ATRA) helps in maturation and it is the only leukemia which can be treated with a vitamin so it's pretty cool and maybe that's why examiners would like to ask it!
Pro is associated with a translocation and it is the only one among these which is high yield.
ACUTE has 5 alphabets and MYELOID has 7 alphabets so just add 1 in front of the numbers and you know - Acute promyelocytic leukemia t(15;17)
Mono has a lot of big O's so mono is the big one, myelo (like a small kid, Milo, with one O) is the small one. So myelomonocytic has the small number, M4 and monocytic has the bigger number, M5.
I made this association to remember gum infiltration is seen in M5: You make big bubbles while chewing gum. They look like O's and big O's should remind you of Acute mOnOcytic leukemia.
Acute erythroid leukemia has precursors which may show coarse granular cytoplasmic positivity with the Periodic-acid-Schiff (PAS) stain.
RBC PAS: Six alphabets, hence M6? Pass me some RBCs ^__^
Platelet has 8 alphabets, the AML classification goes till M7 so you can remember that way too!
Platelets and fibrin will help you associate acute megakaryoblastic leukemia with myelofibrosis in the bone marrow.
For Auer rods, here's my tick to remember -
M0 and M1 (symbol mnemonic, see image) don't have rods.
I remember that mono is fat and it wouldn't like to have anything that pokes it inside (like a rod).
So anything with mono (M4 and M5) doesn't have rods.
RBCs and platelets (M6 and M7) don't have Auer rods.
That leaves M2 (mature) and M3 (Pro).. They have Auer rods!
That's all!
Pray that I do well in my exams.
-IkaN
As you go from M0 to M7, the cell is getting more and more differentiated.
WBCs, RBCs and Platelets is the order (wrap!)
 |
| French American British classification of Acute Myeloblastic Leukemia (AML types) mnemonic |
Pro has 3 alphabets and so it's M3.
Other 3 letter words you should be familiar with PRO are DIC and VIT.
Acute promyelocytic leukemia is associated with disseminated intravascular coagulation (DIC).
All trans retinoic acid (ATRA) helps in maturation and it is the only leukemia which can be treated with a vitamin so it's pretty cool and maybe that's why examiners would like to ask it!
Pro is associated with a translocation and it is the only one among these which is high yield.
ACUTE has 5 alphabets and MYELOID has 7 alphabets so just add 1 in front of the numbers and you know - Acute promyelocytic leukemia t(15;17)
Mono has a lot of big O's so mono is the big one, myelo (like a small kid, Milo, with one O) is the small one. So myelomonocytic has the small number, M4 and monocytic has the bigger number, M5.
I made this association to remember gum infiltration is seen in M5: You make big bubbles while chewing gum. They look like O's and big O's should remind you of Acute mOnOcytic leukemia.
Acute erythroid leukemia has precursors which may show coarse granular cytoplasmic positivity with the Periodic-acid-Schiff (PAS) stain.
RBC PAS: Six alphabets, hence M6? Pass me some RBCs ^__^
Platelet has 8 alphabets, the AML classification goes till M7 so you can remember that way too!
Platelets and fibrin will help you associate acute megakaryoblastic leukemia with myelofibrosis in the bone marrow.
For Auer rods, here's my tick to remember -
M0 and M1 (symbol mnemonic, see image) don't have rods.
I remember that mono is fat and it wouldn't like to have anything that pokes it inside (like a rod).
So anything with mono (M4 and M5) doesn't have rods.
RBCs and platelets (M6 and M7) don't have Auer rods.
That leaves M2 (mature) and M3 (Pro).. They have Auer rods!
That's all!
Pray that I do well in my exams.
-IkaN
Thank youuuuuu
ReplyDeleteSuper helpful
My pleasure :)
DeleteAwesome thanks
DeleteOMG ahhhhh you saved my life thanks :D
ReplyDeleteYou are a saviour !!
ReplyDeleteI have my finals in 10 days and I've been memorising this classification forever
Thank you ;D
Hahahahha. Glad I made this!
DeleteSame here with the exams!! Good luck to you :D
One more hurdle.. done and dusted by ikan's might.. :)
ReplyDeleteThanks.. and cheers
One more hurdle.. done and dusted by ikan's might.. :)
ReplyDeleteThanks.. and cheers
Hahahahha. You're most welcome, you devilish hurdler! :P
DeleteSeriously .... ! Unbelievably made easier.... thanxxxx dear!! For ur ur efforts thumbs up... can't thank u enuf:-)..
ReplyDeleteThank you, thnak you, thank you! :D
DeleteThank you very much. This is excellent.
ReplyDeleteThanks.
DeleteThis is wonderful
ReplyDeleteThe blog is awesome.... enormously simplified version of that classification great job
ReplyDeleteThank you so much! :)
DeleteMedicowesome is super AWESOME! Thanks so much!!
ReplyDeleteYou're most welcome, super awesome reader :D
DeleteThank you so much
ReplyDeleteBest regards, from Indonesia
You're most welcome <3
Delete(I am not a fish)
Great piece of work there, the trick is just awesome dude.... Keep it up
ReplyDeleteU r awesome :)
ReplyDeleteThanks <3
DeleteAwesome����
ReplyDeleteSUPERB Mnemonic
ReplyDeleteI mean seriously, I din't even know there was an easy way to memorize this thing.Wao.Thank you.
ReplyDeleteTHANK YOU! Your little tricks to remembering are just great!!
ReplyDeleteThis should save my exam
ReplyDeletethanks thanks for these simple ways to remember this classification
ReplyDeleteHey that sounds great!!!! Amazingly enough to remember!
ReplyDeleteOnly useful i found in this is to Remember M3 as PRO 3 letters
ReplyDeleteOther is too confusing to remember