Sunday, June 12, 2016

Hyperthyroidism and hyperdynamic circulation

Hello!

Hyperthyroidism results in a hyperdynamic circulation. This post was created because I attempted to know why :D

The cardiac effects of hyperthyroidism commonly cause increased preload with low systemic vascular resistance, a high heart rate, high cardiac output and increased cardiac muscle oxygen consumption. So that's why, hyperdynamic circulation!


Thyroid hormone has a consistent positive chronotropic effect, and resting sinus tachycardia is the most common cardiovascular sign of human hyperthyroidism.

Why?
Because thyroid hormone results in increased responsiveness to catecholamines.

Why does hyperthyroidism cause reduction in SVR?
The reduction in peripheral vascular resistance is thought to be mediated by decreased responses to contractile stimuli mediated by alpha adrenergic receptors and enhanced responsiveness to beta adrenergic receptor mediated dilatation.

That's all!

-IkaN

Sources:
http://press.endocrine.org/doi/full/10.1210/jcem.87.3.8302
http://circ.ahajournals.org/content/96/2/592.full

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