Saturday, October 29, 2016

Step 2 CK: Treatment of narcolepsy and cataplexy

Treatment of Narcolepsy:
Patients with sleepiness severe enough to require medication can be treated with stimulant medications.

Modafinil - First line pharmacologic therapy for narcolepsy.
Well tolerated.
Illicit use is rare.
MOA: Increases dopaminergic signaling.
Methylphenidate, or amphetamines may be used. Not preferred due to cardiovascular and psychiatric side effects.

Cataplexy:
REM sleep-suppressing medication (eg, venlafaxine, fluoxetine, atomoxetine) - First line therapy for cataplexy.

For patients whose sleepiness or cataplexy does not improve with one of these medications, sodium oxybate may be of benefit.

Source: Uptodate
That's all!
-IkaN

2 comments:

  1. good info! keep posting from utd ���� thankss!!

    ReplyDelete

This is express yourself space. Where you type create something beautiful! <3
Wondering what do I write? Well..
Tell us something you know better. You are a brilliant mind. Yes, you are! ^__^
Ask about something you don't understand @_@?
Compliment... Say something nice! =D
Be a good critic and correct us if something went wrong :|
Go ahead. Comment all you like here! (:

Related Posts Plugin for WordPress, Blogger...