So we will be learning about the structure and multiplication of poxviridae today from the mnemonic: “Pox is in a big box”
Poxviruses are brick-shaped.
The virion is exceptionally large.
They are enveloped.
Poxvirus replicates in the cyptoplasm.
Poxvirus encodes its own machinery for genome transcription, a DNA dependent RNA polymerase, which makes replication in the cytoplasm possible. Most dsDNA viruses require the host cell's DNA-dependent RNA polymerase to perform transcription. These host DNA are found in the nucleus, and therefore most dsDNA viruses carry out a part of their infection cycle within the host cell's nucleus.
Audio and mnemonic by Huzaifa Bhopalwala