Tuesday, May 16, 2017

Cortisol and eosinophils

Today, I forgot the relationship between cortisol and esosinophils. Completely screwed up a practice question because I couldn't remember it.

Now I made a mnemonic to remember this :D

Mnemonic: In hypERcortisolism, Eosinophils Reduce.

Why do corticosteroids cause eosionopenia? Why does hypocortisolism cause an increase in eosinophil count?

The mechanism is obscure but it has to do with a decrease in eosinophil adhesion and migration.

Inhibition of eosinophil adherence and chemotaxis may in part explain how corticosteroids produce eosinopenia and decrease the local accumulation of eosinophils.

You can read more about it here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC371568/

That's all!
-IkaN

Related post: Eosinophilia mnemonic

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