Friday, May 5, 2017

Cryptococcus neoformans notes and mnemonics

Hello!

This post is on cryptococcus neoformans.


Causes: 
Meningoencephalitis in immunocompromised patients

Transmission:
Respiratory (pigeon droppings) and spread hematogenously to the brain.

Morphological features:
Polysaccharide capsule
Wide capsular halo on India ink
Only pathogenic fungus with a polysaccharide capsule
Unequal budding with narrow base

Treatment:
The main antifungal agents used for the treatment of cryptococcal meningitis include intravenous amphotericin B deoxycholate and its lipid formulations, oral flucytosine, and oral fluconazole. Amphotericin B and flucytosine are fungicidal (inhibition leads to cell death), while fluconazole is only fungistatic (ie, inhibits without killing)

Mnemonic:
Add captionCryptococcus neoformans notes and mnemonics
That's all folks!
Cryptococcus reminds me of Mickey mouses' ears at times xD
-IkaN

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