HSP is also known as Anaphylactoid purpura.
• Most common vasculitis in children.
• Most common Leucocytoplastic vasculitis.
It predominantly affects small vessels (venules, capillaries, arterioles).
It is usually self limited but may progress to end stage renal disease.
Clinical features:
1) Skin: rash, palpable purpura (non-thrombocytopenic purpura).
2) Joints: arthritis, arthalgia.
3) Kidneys: glomerulonephritis (proteinuria, hematuria).
° Severe renal failure occurs in about 1-2%, characterized by crescenteric glomerulonephritis which is treated with intravenous methyl prednisolone.
4) GIT : colicky abdominal pain.
On investigation: total Ig A increases.
Renal biopsy: mesangial Ig A deposits.
Treatment: conservative treatment
Oral prednisolone may be given.
Thanks for reading.
Madhuri Reddy.
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