Thursday, January 11, 2018

Henoch Schonlein purpura

HSP is also known as Anaphylactoid purpura.

• Most common vasculitis in children.
• Most common Leucocytoplastic vasculitis.
  It predominantly affects small vessels (venules, capillaries, arterioles).
  It is usually self limited but may progress to end stage renal disease.
 
Clinical features:
1) Skin: rash, palpable purpura (non-thrombocytopenic purpura).
2) Joints: arthritis, arthalgia.
3) Kidneys: glomerulonephritis (proteinuria, hematuria).
  ° Severe renal failure occurs in about 1-2%, characterized by crescenteric glomerulonephritis which is treated with intravenous methyl prednisolone.
4) GIT : colicky abdominal pain.

   On investigation: total Ig A increases.
Renal biopsy: mesangial Ig A deposits.

Treatment: conservative treatment
    Oral prednisolone may be given.

Thanks for reading.

Madhuri Reddy.

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