Hey everyone!
A quick "things to remember" list about Burkitts lymphoma for tests!
- B cell lymphoma (B for Burkitts, B for B cells!)
- All types of Burkitt's lymphoma are characterized by disregulation of the c-myc gene.
- Myc (c-Myc) is a regulator gene that codes for a nuclear transcription factor.
- The most common variant is t(8;14).
- The "starry sky" appearance on histology
- It is due to scattered tingible body-laden macrophages (macrophages containing dead body of apoptotic tumor cells).
The mnemonic *drum roll*
Burkitts lymphoma mnemonic |
That's all!
Lemme know if it helped =)
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