Sunday, July 6, 2014

Intrinsic tyrosine kinase and receptor-associated tyrosine kinase mnemonic

Hello, how is everything going? ^__^
We'll be learning on how to remember some signaling pathways of endocrine hormones =D
Let's get started!

MAP kinase pathway mnemonic:
"I intrinsically try to map growth"
Intrinsic tyrosine kinase - Insulin & growth factors (IGF-1, FGF, PDGF, EGF) - MAP kinase pathway!

JAK-STAT signaling pathway mnemonic:
JAK reminds me of a jack ass. I imagine a jack pig instead =P
Prolactin, Immunomodulators (e.g., cytokines, IL-2, IL-6, IL-8, IFN), Growth hormone.

If you can't remember the immunomodulators, just think STAT!
sTaT has two T's which should remind you of "Tins and Ters"
Tins - Erythropoietin, prolactin, thrombopoietin, leptin
Ters - Interferons, Interleukins

And another animal - rat.
This'll help you remember that it is a receptor-associated tyrosine kinase!

So remember 3 animals - Jackass, pig & rat. You should be good :)

That's all!
Hope you're doing well & see you in the next post =D


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