Thursday, December 11, 2014

Pagets disease of the breast mnemonic


Anybody reading pagets disease of the breast?


Here's everything you need to know about Paget's cells histologically -
Prominent nucleoli
Adenocarcinoma cells
G looks like C for clear cytoplasm
Epithelium of epidermis (Present in epithelium of epidermis)
Transparent surrounding (Appear to lie in a vacuoles)
Secretion vacuoles that contain mucin may be present

Here's the clinical stuff - 
P for Pruritus
At the Areola and nipple
G looks like C for crusting and ulceration (If progresses)
E for Eczema
D for underlying DCIS (Hence, always do a mammogram with skin biopsy!)

That's all!


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