Wednesday, February 4, 2015

Study group discussion: Difference between rouleaux formation and agglutination of RBC's

I was asked in pathology viva, what is the difference between agglutination and rouleaux formation.

I think rouleax is the RBC's sticking to form a tube or a roll and agglutination with an immunological reaction?
Have to check.

Agglutination clumping of RBC due to Antigen - Antibody reaction,
whereas in rouleaux clumping occurs due to decrease negative charge during rouleaux formation stage in ESR.

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