Saturday, February 27, 2016

Glucose in pleural fluid analysis

Hi :)

A low pleural fluid glucose concentration (less than 60 mg/dL, or a pleural fluid/serum glucose ratio less than 0.5) narrows the differential diagnosis of the exudate.

Causes of low glucose in pleural fluid include:

Rheumatoid pleurisy
Complicated parapneumonic effusion or empyema
Malignant effusion
Tuberculous pleurisy
Lupus pleuritis
Esophageal rupture

You don't need to memorize the causes if you know the mechanism: The cause of low pleural fluid glucose is increased utilization of glucose by constituents of pleural fluid, such as neutrophils, bacteria (empyema), and malignant cells.

The lowest glucose concentrations are found in rheumatoid pleurisy and empyema, with glucose being undetectable in some cases :O

Did you know?
Pleura came from the word Pleuron which meant the side wall of each segment of the body of an arthropod. Pleuron was a singular word and pleura was the plural form. But we started using pleura as a singular word for both pleurons... And pleurae is now the word for plural pleura :P

That's all!
Say something nice to yourself today :)

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