For epilepsy patients Stress and anxiety exacerbate the condition by increasing the frequency and severity of attacks!!
The disease produces changes in neuronal signalling that increases seizures by converting a beneficial stress response into an epileptic trigger.
A neurotransmitter involved called Corticotropin- Releasing Factor (CRF) diminishes activity of piriform cortex (seizure- producing part of brain) in normal brain. In diseased condition, CRF does the exact opposite- exciting the activity of piriform cortex, thus increasing seizure attacks!!!
This research points to the possibility that CRF- blocking drugs would prevent stress- induced seizures in epileptic patients.
The disease produces changes in neuronal signalling that increases seizures by converting a beneficial stress response into an epileptic trigger.
A neurotransmitter involved called Corticotropin- Releasing Factor (CRF) diminishes activity of piriform cortex (seizure- producing part of brain) in normal brain. In diseased condition, CRF does the exact opposite- exciting the activity of piriform cortex, thus increasing seizure attacks!!!
This research points to the possibility that CRF- blocking drugs would prevent stress- induced seizures in epileptic patients.
That's all!
-Jaskunwar Singh
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