Treatment of Narcolepsy:
Patients with sleepiness severe enough to require medication can be treated with stimulant medications.
Patients with sleepiness severe enough to require medication can be treated with stimulant medications.
Modafinil - First line pharmacologic therapy for narcolepsy.
Well tolerated.
Illicit use is rare.
MOA: Increases dopaminergic signaling.
Well tolerated.
Illicit use is rare.
MOA: Increases dopaminergic signaling.
Methylphenidate, or amphetamines may be used. Not preferred due to cardiovascular and psychiatric side effects.
Cataplexy:
REM sleep-suppressing medication (eg, venlafaxine, fluoxetine, atomoxetine) - First line therapy for cataplexy.
REM sleep-suppressing medication (eg, venlafaxine, fluoxetine, atomoxetine) - First line therapy for cataplexy.
For patients whose sleepiness or cataplexy does not improve with one of these medications, sodium oxybate may be of benefit.
Source: Uptodate
That's all!
-IkaN
-IkaN
good info! keep posting from utd ���� thankss!!
ReplyDeleteThanks. I will try!
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