Adverse effects of GLUCOCORTICOIDS:
Mnemonic is glucocorticoids itself!
G: Glaucoma (topical use), glycosuria
L: Limb muscle atrophy, myalgia
U: Ulcers (peptic) increased gastric acid secretion, dyspeptic symptoms are high after high dose therapy
C: Cushing's Habitus (rounded face, hump, obesity of trunk with relatively thin limbs, fragile skin,purple striae, easy bruising, telangiectasia, hirsutism)
O: Osteoporosis (specially vertebrae and flat bones) radiological evidence of osteoporosis is an indication for withdrawal of corticosteroid therapy)
C: Cataract (posterior subcapsular)
O: Osteonecrosis (avascular necrosis of femur)
R: Retardation of growth (even with small doses for long periods in children; large doses do inhibit GH secretion) ; Contraindicated in RENAL failure
T: Contraindicated in TB
I: Impaired wound healing and surgical incisions
C: Cutaneous atrophy , contraindicated in CHF
O: Oedema, fOetal abnormalities (cleft palate, our, increased risk of gestational diabetes, pregnancy induced hypertension, preeclampsia
I: Infections ( increased susceptibility to opportunistic infections like Candida)
D: Diabetes mellitus(precipitation), hyperglycemia
S: Suppression of Hypothalamo-pituitary axis
(Well glucocorticoids can cause almost anything)
Submitted by Sarah Azad
Mnemonic is glucocorticoids itself!
G: Glaucoma (topical use), glycosuria
L: Limb muscle atrophy, myalgia
U: Ulcers (peptic) increased gastric acid secretion, dyspeptic symptoms are high after high dose therapy
C: Cushing's Habitus (rounded face, hump, obesity of trunk with relatively thin limbs, fragile skin,purple striae, easy bruising, telangiectasia, hirsutism)
O: Osteoporosis (specially vertebrae and flat bones) radiological evidence of osteoporosis is an indication for withdrawal of corticosteroid therapy)
C: Cataract (posterior subcapsular)
O: Osteonecrosis (avascular necrosis of femur)
R: Retardation of growth (even with small doses for long periods in children; large doses do inhibit GH secretion) ; Contraindicated in RENAL failure
T: Contraindicated in TB
I: Impaired wound healing and surgical incisions
C: Cutaneous atrophy , contraindicated in CHF
O: Oedema, fOetal abnormalities (cleft palate, our, increased risk of gestational diabetes, pregnancy induced hypertension, preeclampsia
I: Infections ( increased susceptibility to opportunistic infections like Candida)
D: Diabetes mellitus(precipitation), hyperglycemia
S: Suppression of Hypothalamo-pituitary axis
(Well glucocorticoids can cause almost anything)
Submitted by Sarah Azad
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