Wednesday, April 5, 2017

Drugs causing Hyperkalemia mnemonic


Lets remember drugs which cause rise in serum potassium levels:

1 - SpironolactONE ( and other potassium sparing diuretics )

3 - TRImethoprim, ACE inhibitors, ARBs, Beta blockers (B = 3) :p

5 - NSAIDs, PENTAmidine, Sulfa drugs

7 - HEParin, cycloSporine

9 - ArgiNINE hydrochloride

Wohhooo... So we have successfully ( SUCCINYLCHOLINE ) memorised the drugs with mnemonic made up of odd digits ( DIGITALIS ) :D

That's all
Happy studying :)

- Jaskunwar Singh

1 comment:

  1. (mechanisms don't fit the mnemonic, included for completeness)
    Drugs That cause HyperK – “Use digits (Digitalis*) to successfully (Succinylcholine**) memorize.
    # Rx Mechanism
    1 SpironolactONE (& other K-spar Diur) Inhib aldo or ENaC Channel
    2 β-2 blockers Interferes with β2-mediated intracellular K uptake
    3 TRImethoprim, Inhib renal tubular Cr Secr, & ENaC
    4 Cyclosporine (FOURine) Blocks aldo activity
    5 PENTAmidine, NSAIDs ↓Renal perfusion ↓K deliv to CD
    6 ACEi + ARB Inhib aldo
    7 HEParin Blocks Aldo Production
    8 Bl∞d Transfusions (pRBCs leak K in storage)
    9 ArgiNINE Hcl Cationic displacement of intracellular K
    * Inhibits Na-K ATPase pump
    **Causes extracellular leakage of K through Ach rcptrs


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