Friday, May 5, 2017

Cryptococcus neoformans notes and mnemonics


This post is on cryptococcus neoformans.

Meningoencephalitis in immunocompromised patients

Respiratory (pigeon droppings) and spread hematogenously to the brain.

Morphological features:
Polysaccharide capsule
Wide capsular halo on India ink
Only pathogenic fungus with a polysaccharide capsule
Unequal budding with narrow base

The main antifungal agents used for the treatment of cryptococcal meningitis include intravenous amphotericin B deoxycholate and its lipid formulations, oral flucytosine, and oral fluconazole. Amphotericin B and flucytosine are fungicidal (inhibition leads to cell death), while fluconazole is only fungistatic (ie, inhibits without killing)

Add captionCryptococcus neoformans notes and mnemonics
That's all folks!
Cryptococcus reminds me of Mickey mouses' ears at times xD


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