Sunday, July 9, 2017

Staphylococcal Scalded Skin Syndrome vs Bullous Impetigo

How do you differentiate Staphylococcal Scalded Skin Syndrome (SSSS) from Bullous Impetigo (BI)?

The exfoliative toxins are restricted to the area of infection in BI. In SSSS, infection is diffuse.

In BI, bacteria can be cultured from the blister contents. Cultures from blisters are negative in SSSS.

Blood cultures are usually negative in SSSS (positive in BI).

In SSSS, Nikolsky sign is positive. It is negative in BI.

In BI, patients are usually not ill appearing.

That's all!

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