Saturday, February 17, 2018

Kallman syndrome mnemonic

Kallman Syndrome (also known as Olfactogenital dysplasia/syndrome or anosmic idiopathic hypogonadotropic hypogonadism)

Let's​ get down with the mnemonics!

'Kallman' kinda rhymes with 'Tallman', right? Well, "man" for it's more common in boys and Tall these individuals are of normal or even increased height (Tall).

The other features are:

K - kinda looks like an X so it's X-linked
K also sounds like C for Colorblindness
A - anosmia
L - lip (cleft lip and cleft palate)
N - nerve deafness
A - ataxia (cerebellar ataxia)
M - midline defects (cleft palate, cleft lip)

Other important points are:
- The defect is in the KAL gene which codes for the protein anosmin.
- It can be due to autosomal dominant or recessive inheritance.

That's all!

Stay awesome 

This post is written by Nikhil as part of the MSGAI.


  1. Hey nice mnemonic but kallman and de morsier syndrome are not same.

  2. Your website is awesome!
    Btw i'm with DF on this.
    Kallmann isnt X-linked?!??

    1. Thank you, updated the post.

      Kallmann syndrome (KS) is characterized by hypogonaotropic hypogonadism and anosmia; it can occur sporadically or be inherited as X-linked, autosomal dominant or autosomal recessive forms. Source:
      Dodé, C., Hardelin, JP. Kallmann syndrome. Eur J Hum Genet 17, 139–146 (2009).


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