Neurology Nuggets : Trigeminal neuralgia in Multiple Sclerosis.

Hello everybody!

A short nugget to start your Day with.

Let's see the reason behind the occurrence of Trigeminal Neuralgia in Multiple Sclerosis.

Multiple Sclerosis is basically a disorder of oligodendrocytes - derived Myelin which leads to blocks of varied degrees in Nerve impulse conduction.

The Trigeminal nerve is myelinated by Schwann cells, like rest of the Peripheral nervous System.
But still we see a high frequency of Trigeminal Neuralgia in Multiple Sclerosis.

The reason for this is-

*The trigeminal nerve is ensheathed by oligodendrocytes - derived myelin, rather than Schwan cells - derived myelin for upto 7mm after it leaves the Brainstem.*

This explains the high frequency of Trigeminal Neuralgia in Multiple Sclerosis which is a disorder of oligodendrocyte myelin.

Let's Learn Together!
-Medha Vyas.