Hello
everyone ..
I
make mnemonics for some important side effects of oral hypoglycemic
drugs.
You
must know that because you may prescribe it for 1 out of 11 adults in whole
population the of world….!!
Side effects of Oral hypoglycaemic drugs along with
it's class & mechanism of action
#Mnemonic 1
Big Men ForminG Poor Diabetic neuropathy ( D/Dx B12 Deficiency ➡️ confirmed by
doing B12 LAB test.)
Biguanide = Metformin
Inhibit
mGPD
It
causes Vitamin B12 Deficiency & Lactic
Acidosis (LA)
#Mnemonic 2
1st Key to SUccess
is Lord "Ram"
1st Gen SUlfonylureas
Closes K+ Channel
Ram = Disulfiram
like reaction….
#Mnemonic 3
Paragliding makes your heart failed or maybe a fracture or bladder injury
Para = PPAR Y
Gliding = Glitazone
activates it...
#Mnemonic 4
"Rosy red Blood don't reach to
heart (MI) but goes into Pee = Red Pi ( Pee = Urine in Bladder Cancer )
MI
(rosiglitazone)
Bladder
cancer (pioglitazone)
#Mnemonic 5
“Change
your Daily Personal Passivity (DPP) otherwise
your heart fails”
DPP = DPP-4 inhibitors
#Mnemonic 6
“Candid Status is Very Good in Love Test”
SGLT-2 inhibitors can cause Vulvovaginal Candidiasis
Drugs category & their Suffix
Pramlintide = Amylin
Analogue
1st
gen Sulfonylureas = “Amide”
2nd
gen Sulfonylureas = “Ride” & “Zide”
Meglitinides
= “Nide”
DPP-4
Inhibitors = “Gliptin”
Glitazones / thiazolidinediones
= “Zone”
SGLT
-2 Inhibitors = “Flozin”
#Mnemonic 7
Alpha glucosidase
inhibitors = "Please Side your Car & Pay Toll"
Acarbose & Miglitol
#Clinical Pearls
Weight neutral = DPP 4 & Alpha Glucosidase
inhibitors
SGLT2 inhibitors & GLP-1 = Used in CVD
( Cardiovascular diseases) patients
In case of Renal failure you can only give 2 type of
drugs orally = DPP 4 inhibitors & Glitazones
Injectables can be given in renal failure.
3 times / day dosing = Pramlintide , Alpha
Glucosidase inhibitors & Glinide
Regular Insulin ( Short acting ) is preferred
for
DKA ( IV)
Hyperklaemia (Add Glucose)
Stress Hyperglycemia
Thank you :)
- Dr. Drashtant Prajapati
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