Sunday, September 27, 2020

Mnemonic for cancers which have “BRAF” gain of function mutation

Hello everyone ! 

Mnemonic : 

BRAin MEETS NPH ! ( Correlate with NPH- Normal Pressure Hydrocephalus) 


ME = Melanoma ( BRAF-V600E ) 

TS = Threonine/ Serine Kinase ( BRAF gene product ) 

N = Non Hodgkin Lymphoma 

P = Papillary thyroid Carcinoma , Polyp ( Serrated ) 

H = Hairy Cell Leukemia 

Small molecular inhibitors of BRAF oncogene positive Melanoma = Dabrafenib & Vemurafenib

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