Thursday, May 27, 2021

Immunofluorescence patterns in glomerular diseases notes and mnemonics

Immunopathologic patterns of immunoglobulins (Igs) and/or complement components deposited in glomerular diseases notes and mnemonics

Linear deposition:
Anti-GBM disease (mainly IgG)
unspecifically IgG in diabetes mellitus

Granular deposition: 
membranoproliferative GN
post-infectious GN
membranous GN
IgA, IgM, C1q, C3

Pauci immune deposition:
Granulomatosis with polyangiitis (Wegener) PR3-ANCA/c-ANCA
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)
Microscopic polyangiitis MPO-ANCA/p-ANCA

Love,
IkaN 

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