In the SYNTAX (Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery) trial, patients with 3-vessel and left main coronary artery disease (LMCAD) treated with coronary artery bypass graft surgery (CABG) compared with percutaneous coronary intervention (PCI) with first-generation drug-eluting stents (DES) had lower 5-year rates of death, myocardial infarction (MI), stroke, or unplanned revascularization.
Patients with low SS (≤22) had an equivalent prognosis after PCI and CABG, whereas patients with high SS (≥33) had improved event-free survival with CABG. Patients with intermediate SS (23–32) and multivessel disease tended to do better with CABG, whereas PCI seemed to be an acceptable treatment alternative for patients with intermediate SS and LMCAD.
-IkaN
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