Monday, June 2, 2014

Lecithin–sphingomyelin ratio mnemonic

Hey everyone!

We measure the L:S ratio in the amniotic fluid to check for fetal lung maturity.

The concentration of lecithin and sphingomyelin is equal till 32–33 weeks gestation after which the lecithin concentration begins to increase significantly while sphingomyelin remains nearly the same.

An L:S ratio of 2 or more indicates fetal lung maturity and a relatively low risk of infant respiratory distress syndrome, and an L/S ratio of less than 1.5 is associated with a high risk of infant respiratory distress syndrome.

Not something you forget, but this is how it plays in my head - Phosphatidylcholine Peaks, Sphingomyelin remains the Same.

It also helps you remember that lecithin is made up of phospholipids like phosphatidylcholine.
(Sometimes, examiners may use basic biochemical compounds to test whether you know what they are made of.. That's when you show them what you are made of as well B)

That's all!

-IkaN

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