Here's a short post on important points in diagnosis of Buerger's disease (don't confuse the name with Berger's disease which is IgA nephropathy) also known as Thromboangiitis obliterans.
- Recurrent inflammation and thrombosis of small and medium sized vessels
- Hands and feet are affected the most
- Vasculitis and ischemia (causing blackish discoloration of skin)
- Chronic smoking (a definite predisposing/ risk factor)
Clinical features and diagnostic criteria:
- male patient 30-40 years of age
- history of chronic tobacco use
- Angiography: - cock- screw appearance of arteries of wrists and ankles
- tree root/ spider leg appearance due to collateral circulation
- Exclusion of other vascular diseases ( Raynaud's phenomenon, atherosclerosis, diabetes, hypertension, endocarditis, hypercoagulable states, auto-immune disorders) is important.
- Skin biopsy (rare)
Note: A possible Rickettsial infection (mostly Rickettsia rickettsiae) could be there which adds on to the pathology of the disease! (usually in cases of amputation of the affected area)
- Jaskunwar Singh