Wednesday, February 22, 2017

Fact of the day: Muscle relaxant of choice during anaesthesia in renal and hepatic failure

Did you know? Atracurium, cisatracurium, and mivacurium have theoretical advantages for patients with hepatic or renal failure because these drugs undergo extensive plasma degradation. 
Atracurium is metabolized by a combination of spontaneous degradation in plasma (Hofmann elimination) and ester hydrolysis by plasma esterases.

-IkaN

4 comments:

  1. Wait, but the drugs mentioned are neuromuscular blocking agents, correct? So wouldn't they only have a paralytic effect and still need adjunctive anesthesia (sedation, analgesia)?

    ReplyDelete
    Replies
    1. Oh yes, I changed the posts title to make it more accurate in the literal sense :)

      Delete
  2. These are not muscle relaxers these are NMBAs...Nimbex is usually DOC anyways. No offense

    ReplyDelete
    Replies
    1. "Atracurium, a nondepolarizing muscle relaxant..."
      https://www.ncbi.nlm.nih.gov/pubmed/3755306

      Delete

This is express yourself space. Where you type create something beautiful! <3
Wondering what do I write? Well..
Tell us something you know better. You are a brilliant mind. Yes, you are! ^__^
Ask about something you don't understand @_@?
Compliment... Say something nice! =D
Be a good critic and correct us if something went wrong :|
Go ahead. Comment all you like here! (:

Related Posts Plugin for WordPress, Blogger...