Did you know? Atracurium, cisatracurium, and mivacurium have theoretical advantages for patients with hepatic or renal failure because these drugs undergo extensive plasma degradation.
Atracurium is metabolized by a combination of spontaneous degradation in plasma (Hofmann elimination) and ester hydrolysis by plasma esterases.
-IkaN
Atracurium is metabolized by a combination of spontaneous degradation in plasma (Hofmann elimination) and ester hydrolysis by plasma esterases.
-IkaN
Wait, but the drugs mentioned are neuromuscular blocking agents, correct? So wouldn't they only have a paralytic effect and still need adjunctive anesthesia (sedation, analgesia)?
ReplyDeleteOh yes, I changed the posts title to make it more accurate in the literal sense :)
DeleteThese are not muscle relaxers these are NMBAs...Nimbex is usually DOC anyways. No offense
ReplyDelete"Atracurium, a nondepolarizing muscle relaxant..."
Deletehttps://www.ncbi.nlm.nih.gov/pubmed/3755306