Sunday, March 24, 2013

HLA, MHC & CD T cell mnemonic

Hello everyone!
Time for another immmunology mnemonic =D

MHC class I:
CD8+ T-cells recognize MHC I.
It takes only 1 stroke of the pen to write “8

The genes have only one alphabet. (HLA-A, HLA-B, HLA-C)

CD8 x MHC1 = 8
CD8+ are Cytotoxic T cells because "EighT" has T for "Toxic"

All cells have one nucleus, so all nucleated cells have class I MHC.

MHC I has one chain (alpha chain) & one microglobulin (Beta 2 microglobulin).
MHC class II:
CD4+ T-cells recognize MHC II.
It takes 2 strokes of the pen to write “4″

The genes have two alphabets. (HLA-DP, HLA-DQ, HLA-DR)

CD4 x MHC2 = 8
CD4+ are Helper T cells because “Cells ask for (four, 4) help

MHC II has two chains. (One alpha & one beta.)

That's all!
Have a lovely week <3


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