Saturday, July 2, 2016

Cronkhite Canada syndrome

Cronkhite Canada syndrome

1. Non hereditary GI polyposis
2. Usually seen after 50 years of age.
3. Associated with alopecia, nail atrophy and hyperpigmentation.
4. Histology similar to juvenile polyps.
5. Intervening mucosa shows dilated glands (c/w Juvenile Polyps)
6. Patients present with abdominal pain, weight loss, diarrhea. Most patients die of cachexia.
7. Rare cases show transformation into Carcinoma colon.

Related post: Polyposis syndrome mnemonic

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