Wednesday, August 2, 2017

Asthma + Eosinophilia

Let us suppose that a patient has the classic signs & symptoms of Asthma and with that she has eosinophilia ( Absolute eosinophil count above 500/mm3).

The next step should be to look at the serum IgE levels.

If it is also elevated-

1. Do a stool examination and serological testing for strongyloidiasis.

2. Do Aspergillus-skin testing and check for aspergillus specific IgE.

If you have got a positive result for one of the above two, you have your diagnosis.

But what if both of the above results come out to be negative.

Then consider Churg Strauss syndrome or Eosinophilic granulomatosis with polyangiitis.

That's it!

-VM

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