The criteria are met in an individual if two or more of the features listed are present.
The mnemonic is "FANCOOL"
F: Family history
A: Axillary freckles (known as CROWE'S SIGN)
N: Neurofibromas (2 or more)
C: Café-au-lait macules (6 or more)
O: Optic gliomas
O: Osseous (sphenoid dysplasia)
L: Lisch nodules in the eyes.
Thanks for reading.
Madhuri
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