Hello everyone....
A diabetic patient who is taking NPH insulin regularly at early evening time presents with early morning headache. He also feels very stressed & tiredness.
I have checked that he is hyperglycemic.
Suddenly I think about Dawn & Somogyi phenomenon. But I have a confusion between that 2 terms.
So I make a mnemonic…
Here it is ..
Dawn & Somogyi phenomenon
In both Early Morning High Glucose
= Due to ⬆️ GH & Cortisol Surge
What is the difference ??
but if you give high dose = Risk of SomOGYi ..!!
Secondary to Excessive Night Insulin Dose in SomOGYi= HypOGLYcemia at 3 AM
Normally NPH action is maximal in late evening & middle of night & minimal in early morning.
So patient is taking NPH insulin too early because of that he has normoglycemia at bedtime & Nocturnal hypoglycemia & Early morning Hyperglycemia even before breakfast.
So what is the solution for this patient ?
Shift the time from early evening to before bedtime.
Or Shift the type from NPH to Insulin Glargine / Detemir ( Longer acting & flatter profile ).
Read detailed explanation by awesome IkaN here...
https://www.medicowesome.com/2015/02/somogyi-effect-and-dawn-phenomenon-in.html
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