Wednesday, October 18, 2023

Mnemonic | Morphology of Membranoproliferative Glomerulonephritis

Here again I am back with another mnemonic to remember the morphology of Membranoproliferative Glomerulonephritis 

Pathology is fun πŸ˜­πŸ˜‚

I hope the feelings are obvious to everyone now lol 😁


this mnemonic will be mainly derived from the name of the disease:

Membrano proliferative Glomerulonephritis:

  • if I abbreviate this disease to MG (membranoproliferative glomerulonephritis), than i can make you remebr that MG is a car manufacturing company so its cars would make a tram track appearance on roads when they are driven

and then comes the breakdown of the disease name:

  • Membrano = meaning something wrong is with basement membrane of glomerular capillaries

tram track appearance 


  • Proliferative  = meaning something is proliferating 

so endothelium, mesangium is proliferating (ME from membrano)


  • Glomerulonephritis = inflammation indicates infiltration of leukocytes as it is a nephritic syndrome mainly


specific types of Membranoproliferative glomerulonephritis have these all above said features but certain differences which are mentioned in this table below:

Differences

Membranoproliferative glomerulonephritis type 1

 

Membranoproliferative glomerulonephritis type 2

(C3 glomerulopathy)

Dense deposit disease

C3 deposits

 

Deposited in irregular pattern

(subendothelial ONLY)

 

 

Waxy deposits

(mesangial, subendothelial and tubular BM)

 

Ribbon like highly dense deposits

(mesangial, subendothelial and tubular BM)

Classic complement system components

 

Present

 

Absent

 

Absent


I hope this was fun also for you like always!

I hope it works you again

In Sha Allah!

Thank you πŸ’“

feel free to ask any study related question in the comment sectionπŸ‘½

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