Wednesday, October 18, 2023

Mnemonic | Morphology of Membranoproliferative Glomerulonephritis

Here again I am back with another mnemonic to remember the morphology of Membranoproliferative Glomerulonephritis 

Pathology is fun πŸ˜­πŸ˜‚

I hope the feelings are obvious to everyone now lol 😁


this mnemonic will be mainly derived from the name of the disease:

Membrano proliferative Glomerulonephritis:

  • if I abbreviate this disease to MG (membranoproliferative glomerulonephritis), than i can make you remebr that MG is a car manufacturing company so its cars would make a tram track appearance on roads when they are driven

and then comes the breakdown of the disease name:

  • Membrano = meaning something wrong is with basement membrane of glomerular capillaries

tram track appearance 


  • Proliferative  = meaning something is proliferating 

so endothelium, mesangium is proliferating (ME from membrano)


  • Glomerulonephritis = inflammation indicates infiltration of leukocytes as it is a nephritic syndrome mainly


specific types of Membranoproliferative glomerulonephritis have these all above said features but certain differences which are mentioned in this table below:

Differences

Membranoproliferative glomerulonephritis type 1

 

Membranoproliferative glomerulonephritis type 2

(C3 glomerulopathy)

Dense deposit disease

C3 deposits

↑

 

Deposited in irregular pattern

(subendothelial ONLY)

 

↑↑

 

Waxy deposits

(mesangial, subendothelial and tubular BM)

↑↑↑

 

Ribbon like highly dense deposits

(mesangial, subendothelial and tubular BM)

Classic complement system components

 

Present

 

Absent

 

Absent


I hope this was fun also for you like always!

I hope it works you again

In Sha Allah!

Thank you πŸ’“

feel free to ask any study related question in the comment sectionπŸ‘½

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