Monday, May 17, 2021

Internal Medicine residency program Excel sheet (2020)

Hi guys,

I am sharing an excel sheet containing 200+ Internal Medicine residency programs. Feel free to download it and edit the information and programs according to your profile and needs. There may be a few IMG friendly programs that are missing, so do your homework and don't apply blindly. Use this as a template sheet to work on!

Kindly note, the comments are subjective, and none of the authors endorse them as proven facts. Some information may be incorrect as a lot of manual labor went into making this sheet.

Hope this helps in making the ERAS application process easier!

https://docs.google.com/spreadsheets/d/1l2Vra6wDcZX5_FMLOFcetZua64wwNsdXKDKB0saGykg/edit?usp=sharing




Sunday, May 16, 2021

HERPANGINA vs HERPETIC GINGIVOSTOMATITIS


HERPANGINA

(Hand-Foot-Mouth Disease) 

HERPETIC GINGIVOSTOMATITIS

CAUSATIVE VIRUS 

Coxsackie A virus

Herpes Simplex type 1 virus (HSV-1)

AGE 


3-10 years

6 months-5 years

CLINICAL                             PRESENTATION                  


Grayish Vesicles on                Posterior Oropharyn   

(soft palate, tonsils,

tonsillar pillars, Uvula)                    

                                      


Clusters of vesicles on       Anterior Oropharynx

(Lips, buccal mucosa, tongue, gingiva, hard palate)


TREATMENT                                                                    

                                              


Supportive management with oral hydration and analgesics

Oral Acyclovir


Fact of the day - halothane hepatotoxicity

 Hi!

A patient with biliary stones who's undergone laparoscopic cholecystectomy may develop signs of hepatotoxicity between 2 days - three weeks post-op. due to halothane. The mechanism is this anesthetic's biotransformation to reactive metabolites through P450.

At risk category of patients are females more than 40 years of age.
Labs show elevated AST and ALT.
Hepatitis is relatively rare.

Other effects:

- Cardiac arrhythmias

- malignant hyperthermia

- hypertension


That's all

- Jaskunwar Singh

Thursday, May 13, 2021

Levetiracetam - pregnancy considerations

 Hi!


Levetiracetam, used primarily for seizures control, is also used off-label for SAH, status epilepticus, seizure prophylaxis in craniotomy and traumatic brain injury.


Dosing is increased in pregnancy and closely monitored regularly due to various physiologic effects, especially in third trimester. (levitate dose of levetiracetam) :-

- increased volume of distribution, Vd (increase in plasma volume, CO)

- increased renal excretion (increase in GFR; levitate the rate)

- rapid and almost complete absorption via GIT  (unlike other drugs with decreased absorption in pregnancy)

- low risk of adverse effects and fetal malformations when used in monotherapy. (low with mono, high with poly)

- Levetiracetam is NOT metabolized by liver; Cyt P450 independent. Bioavailability 100%. (unlike other antiepileptics - hepatic metabolism increases in pregnancy)


Levetiracetam crosses placenta and can be detected in the newborn. (leve leaves mother)

The newborns are at greater risk of SGA and low APGAR score.


Protein-binding of the drug is low (<10%). So, decrease in albumin concentration during pregnancy does not significantly affect the drug concentration. (low pro)


That's all

- Jaskunwar Singh

Glomerulonephritis associated with infectious diseases mnemonic


Hepatitis B: Membranous glomerulonephritis
Hepatitis C: Membranoproliferative glomerulonephritis
HIV: Focal segmental glomerulosclerosis

By IkaN

Embryology of eye mnemonic

Hello friends!

Here's is the simplest way to remember embryology of eye.

*Out of all layers (ecto,meso, endo), the endoderm doesn't contribute to the embryology of eye.
* Mesoderm forms - extraocular muscles
* Rest of the structures are derived from ectoderm.

* Surface ectoderm forms the structures which are visible to us from outside like Corneal epithelium
Conjunctival epithelium
 Lacrimal gland
 Lens ( important)

*Neuroectoderm forms neural structures like
Retina
Ciliary body ( not muscles)
Iris - both sphincter and dilator pupillae
Optic nerve

* Neural crest derivatives are 
Meninges of optic nerve
Schwann cells
Ciliary ganglion
Ciliary muscles 

For the remaining derivatives, watch the following picture.

Thank you.
Dr. Madhuri Reddy. 

Wednesday, May 12, 2021

Kartagener syndrome mnemonic

 Hi!

Kartagener syndrome (primary ciliary dysfunction, aka immotile cilia syndrome) mnemonic :-

Tuesday, May 11, 2021

Toxoplasmosis classic triad mnemonic

 Hi!


Toxoplasmosis classic triad in neonates mnemonic: CATS 

- CAlcifications (intracranial)

- Tension hydrocephalus

- See (Chorioretinitis)


Also, check out this video mnemonic by IkaN


- Jaskunwar Singh


ARDS management mnemonic

 Maintenance “DOSE”

Dry Lungs - “Dry lungs -Happy lungs”

  • Maintain negative fluid balance to reduce pulmonary edema

Open but not Over-distended 

Sunday, May 9, 2021

Management of asymptomatic carotid atherosclerotic disease and carotid artery stenosis mnemonic

Super short post!

A) Asymptomatic

≥80% stenosis: Carotid endarterectomy
≤79% stenosis: Medical management

Mnemonic AGES: Asymptomatic Greater than Eighty Surgery

B) Symptomatic

≥70% stenosis: Carotid endarterectomy

Mnemonic SSS: Symptomatic Seventy Surgery

50%-69% stenosis
Male: Carotid endarterectomy
Female: Medical management

Mnemonic MMM: Males Manage More than fifty with surgery

<50% stenosis: Medical management

That's all!
-IkaN

Saturday, May 8, 2021

Creatinine clearance in elderly - basic notes

 Hi!


Elderly people have a decrease in creatinine clearance (CrCl), which means an increase in serum Cr. It is observed that annual rate of this decrease in CrCl is approximately 1 ml/min. after the age of 50 years.

Therefore, it is important to calculate the dose and dosing intervals of nephrotoxic drugs (eg., aminoglycosides) in these patients in order to prevent the precipitation of ARF.

In general,

CrCl <100 ml/min is abnormal.

However, CrCl <10 ml/min signifies the onset and worsening of acute renal failure.

Note -

• GFR is directly proportional to CrCl.

• GFR decreases by age, but not always accompanied by rise in Cr.

• Cockcroft-Gault formula is commonly referred to for calculating CrCl.

CrCl = (Ucr × V)/Pcr (~GFR)

• Double the Cr = Half the GFR.


Note that those patients with signs of worsening diabetes and resulting glomerulopathies, an increase in both GFR and CrCl is seen, which thus causes hyper filtration injury. 


That's all

- Jaskunwar Singh

Rigler's triad mnemonic

 Hi!

Rigler's triad in gall stone ileus mnemonic:

GALL in GIT

Belimumab mnemonic

What is belimumab?

Belimumab is a  monoclonal antibody directed against soluble B lymphocyte stimulator (BLyS).

Belimumab is used in the treatment of? 
Systemic Lupus Erythematosus (SLE)

Mnemonic: Belly Selly SLE (rhymes! sing it enough times and you will never forget)

At present, belimumab is indicated as add-on therapy in adults with active, antinuclear antibody or anti-dsDNA-positive SLE with a high degree of disease activity in the skin and/or musculoskeletal systems that remain moderately to severely active despite optimized standard immunosuppression. 

Patients with severe lupus nephritis or active CNS lupus are not the candidates for belimumab.

That's all!
-IkaN