Saturday, November 1, 2014

Hormones that have similar structure and thus clinical effects

In Addison's disease, increase in ACTH causes hyperpigmentation because it is similar to MSH.

HCG and TSH:
Patients with choriocarcinoma can present with hyperthyroidism. It's because HCG is similar to TSH.

Pitocin and pitressin:
The drug oxytocin can cause water retention because it is similar to vasopressin.

These are all I can think of for now, lemme know if you guys know any other hormones that are so similar that they are able to cause similar effects in our body.


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    1. Omg this is like one of the best compliments ever. Thank you so much!

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  2. ACTH is not similar to MSH, they only come from the same precursor protein POMC, which is cleaved into ACTH and MSH, i.e., they are formed together so the increase in ACTH will cause MSH to increase.
    You can give someone long term ACTH without interfering with their pigmentation, no?

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