COVID-19 and the increased risk of Parkinson's disease

Hi!

Currently posted in psychiatry, I was reading articles on Parkinson's disease and came through this important finding in context with the coronavirus disease.

Guidelines for management of gout by ACR 2020

 Hi!

Long time..

Urate-lowering therapy indications and important guidelines for management of gout, as updated by ACR in 2020:

Mechanical ventilation

Terms you need to know

1.       PaO2: Oxygen saturation in arterial blood  (N = 80-100)

2.       PaCO2: Carbon Dioxide saturation in arterial blood (N = 35 – 45)

3.       FiO2: Fraction of inhaled O2 (N = 21% i.e. the fraction of O2 in atmosphere air which we inhale)

4.       PEEP: Positive End Expiratory Pressure – The pressure needed at the end of expiration to keep the alveoli open.

5.       RR: Respiratory rate (N = 12-16)

6.       TV: Tidal Volume (N = 6-8 ml/kg = approx. 500 ml)

Blood Donation

BLOOD DONATION

PRE-DONATION

HISTORY:

• Men can donate safely once every three months while women can donate every four months
• Age between 18 and 60 years
• The donor should be in a healthy state of mind and body
• Past one year - not been treated for Rabies or received Hepatitis B immune globulin
• Past six months - not had a tattoo, ear or skin piercing or acupuncture, not received blood or blood products, no serious illness or major surgery, no contact with a person with hepatitis or yellow jaundice.
• Past three months - not donated blood or been treated for Malaria
• Past one month - had any immunizations
• Past 72 hours - had dental work or taken Aspirin
• Past 48 hours - taken any antibiotics or any other medications (Allopathic or Ayurveda or Siddha or Homeopathy)
• Past 24 hours - taken alcoholic beverages
• Presently - not suffering from cough, influenza or sore throat, the common cold
• Women should not be pregnant or breastfeeding her child or menstruating.
• No diabetes, chest pain, heart disease or high BP, cancer, blood clotting problem or blood disease, unexplained fever weight loss, fatigue, night sweats, enlarged lymph nodes in armpits, neck or groin, white patches in the mouth, etc.
• No history of TB, bronchial asthma or allergic disorder, liver disease, kidney disease, fits or fainting, blue or purple spots on the skin or mucous membranes, received human pituitary - growth hormones, etc.

EXAMINATION:

• Temperature - Normal (oral temperature not exceeding 37.50 C)
• Pulse - between 50 and 100/minute with no irregularities
• Blood Pressure -Systolic 100-180 mm Hg and Diastolic 50 - 100 mm Hg
• Bodyweight - not less than 45 Kg
• Hemoglobin - not less than 12.5 g/dL-

Procedure to measure Hb using CuSO4:

i) Massage the finger to be pricked (preferably ring finger)

ii) Disinfect it

iii) Prick using disposable needle/ lancet

iv) Put the drop of blood in CuSO4 containing beaker

v) If the blood drop sinks, Hb is more than 12.5, hence the person can donate blood (provided no other contraindication).

PROCEDURE:

• Identify donor and label blood collection bag and test tubes
• Ask the donor to state their full name
• Ensure that:

1. the blood collection bag is of the correct type;
2. the labels on the blood collection bag and all its satellite bags, sample tubes and donor records have the correct patient name and number;
3. the information on the labels matches with the donor's information

• Select a large, firm vein, preferably in the antecubital fossa, from an area free from skin lesions or scars
• Clean the site of venepuncture by alcohol and let it dry
• Perform phlebotomy using a 16-gauge needle, which is usually attached to the blood collection bag. Use of a retractable needle or safety needle with a needle cover is preferred if available, but all should be cut off at the end of the procedure.
• Ask the donor to open and close the fist slowly every 10–12 seconds during collection
• Remove the tourniquet when the blood flow is established or after 2 minutes, whichever comes first
• Ask the patient to squeeze a ball intermittently during the procedure
• Monitor the donor and the donated unit
• Remove the needle and collect samples
• Cut off the needle using a sterile pair of scissors
• Collect blood samples for laboratory testing

POST-PROCEDURE:

DONOR CARE:

• ask the donor to remain in the chair and relax for a few minutes
• inspect the venepuncture site; if it is not bleeding, apply a bandage to the site; if it is bleeding, apply further pressure
• ask the donor to sit up slowly and ask how the person is feeling
• before the donor leaves the donation room, ensure that the person can stand up without dizziness and without a drop in blood pressure
• offer the donor some refreshments

BLOOD UNIT AND SAMPLES:

• Transfer the blood unit to a proper storage container according to the blood center requirements and the product
• Ensure that collected blood samples are stored and delivered to the laboratory with completed documentation, at the recommended temperature, and in a leakproof, closed container

REFERENCES:

http://naco.gov.in/blood-transfusion-services-publications

Written by our guest authors HARSH JOGI and AYUSHI GUPTA

Ascitic Tap

Requirements

Written informed consent, Betadine, Spirit, Sterile gloves, Sterile drapes, a 1.5-3.5 cm 20-22 G needle, a 5-20mL syringe is used, 18-20 G needle attached to a non-collapsible tube (can be made by breaking drip chamber of an IV set and putting one end of it in an empty water bottle for therapeutic tap tubing to a sterile collection bag)

Procedure:

1. Follow universal precautions. 

2. Skin around the site of puncture to be disinfected with betadine or Chlorhexidine and spirit and draped with sterile drapes.

3. Position: The patient should be in supine position( can be asked to roll slightly to left)

4. Site: a) At the junction of medial two-third and lateral one-third of the line join umbilicus and left Anterior superior iliac spine (left side is preferred over right to avoid damage to caecum)

OR 

b) 4 inches above iliac crest, whichever is more dependent

Site has to be lateral to rectus muscle. Avoid areas of scar.

5. Local Anaesthesia:

a) Skin, subcutaneous tissue, abdominal wall layers up to parietal peritoneum to be anesthetized with 2% lidocaine filled syringe using a 22-25 G needle.The needle is advanced into the subcutaneous tissue aspirating every 2-3 mm prior to injecting. 

b) Once a loss of resistance is felt and peritoneal fluid is drawn into the syringe, it indicates that we have entered the peritoneal cavity. Additional lidocaine is then injected to anesthetize the pain-sensitive parietal 

peritoneum. 

(A total of approx. 4-5 ml lidocaine is adequate.) 

c) The needle is then withdrawn. 

6. Puncture: 

For diagnostic tap – a 1.5-3.5 cm 20-22 G needle attached to a 5-20mL syringe 

is used. 

Technique – The aim is to prevent leak by ensuring the skin puncture site is 

not directly over the puncture site into the peritoneal cavity. 

 Z track technique – Pull skin about 2 cm downward before puncturing 

skin→ then leave the skin after entering few mm so as to form a Z

OR 

prick the skin, go for some distance in the subcutaneous plane and then change the angle to vertically downwards to enter the peritoneal cavity.  

For therapeutic tap - A large bore 1.5-2 cm 16-18 G needle is used instead.The syringe is detached and the needle is attached to a non-collapsible rubber tubing.The ascites fluid is drained slowly through the rubber tubing connected to the needle into a sterile collection bag. 

7. Seal : After the puncture, the punctured skin is sealed with a tincture benzoin 

seal. 

8. Post procedures: T.P.R, B.P to be recorded half hourly and the 

patient should not be given feeds for the next 4 hours. If there is pain, analgesics may be given.

- Mitali shroff

CNS practical higher examination function.

This is the first video of the series - Neurology practical examination.

GCS Glasgow Coma scale video

In this video, I'll be talking about GCS. Please do give your comments regarding the video.

GCS explained

By Ojas Gite

Gerstmann's syndrome physical examination

 Gerstmann's syndrome is caused by lesions in the dominant parietal lobe (usually left).

Shingles vaccine

What do we know about the Shingrix Vaccine?

This vaccine is recommended for patients over the age of 50 years. It is a live attenuated vaccine. It is a

recombinant vaccine containing the glycoprotein E named RZV or Shingrix. Two doses are

required 2-6 months apart and can be safely given with influenza (flu) vaccine. History of chickenpox or varicella zoster doesn’t determine whether to give the vaccine or not because antibodies gained through the infection wanes with time.

Lover's heel

Lover's heel is a term used for Gonococcal tenosynovitis of the Achilles tendon given the sexually transmitted nature of gonorrhea.

I just wanted to share this interesting fact with you.

-IkaN

Anion Gap

What is Anion Gap?

We need an equal amount of anions and cations to keep the body electrically neutral. So anion gap is not a real thing, it is just a diagnostic concept. Remember, in cations, we mainly measure Na, the other ‘unmeasured’ but important cations are K, Mg, Ca. Unmeasured means not routinely measured. In anions, we routinely measure Cl- and HCO3-, others important but ‘unmeasured’ anions are PO4, Sulfate and  Albumin.

The formula: Anion gap=Na-Cl-HCO3

(normally 8-16meq) is calculated mostly in metabolic acidosis as either normal anion gap or increased anion gap.

Now the most important thing to always remember is that, if due to anyreason, HCO3 or Chloride (measured anions) decreases, the relative concentration of unmeasured anions will increase, as if the unmeasured anions are trying to compensate the loss of their fellow measured anions by increasing their own concentration 

             In Metabolic Acidosis, HCO3 is low, assume that Na is unchanged for now,  so due to low HCO3, other anions like Cl-( measured) and other unmeasured anion will try to compensate by increasing themselves. If Cl- can increase to replace to loss of HCO3’s negative charge, the anion gap will remain within normal limits, if Cl- is too low and can't compensate, then, by the formula AG=Na(normal)- Cl(low)-HCO3(low), The Anion Gap will increase.

- Vaibhav Jain

Topics to read before PG entrance exams!

Hello Awesomites!

The aim is to help the students who want to give upcoming NEET PG Exam and are clueless about how to plan and prepare ?
I know my friend struggling day in and out for life in Covid wards. Exams doesn't matter now.
When they will have time in hand I want to help them out with plan beforehand. They are already brilliant enough to have been through all the challenges. :)

I know you can't predict what is important for this or next exams. Atleast with time in hand you can glance through some topics that contribute 70% of any exam. I am sharing the list 1st year subject I made during my preparation.

1.ANATOMY

• Embryology 

1. Pharyngeal arches
2. Neural crest derivatives
3. Oogenesis and spermatogenesis
4. Notochord and remnants 
5. Extraembryonic mesoderm
6. Diaphragm 
7. Cardiovascular system ( Abnormal subclavian artery)
8. Urogenital system 

• Histology 

1. Cerebellum
2. Osteoblasts
3. Urinary bladder epithelium
4. Cell junctions
5. Collagen types
6. cartilage
7. Tonsil,Lymph nodes, spleen,thymus
8. Stomach glands
9. Skin with sebaceous glands
10. Connective tissue types
11. Retina 
12. Salivary gland

• NEUROLOGY

1. Fornix 
2. Corpus callosum
3. Cranial nerves and its lesion
4. Brainstem syndromes (lateral medullary )
5. Foramen of skull
6. Facial nerve and trigeminal nerve
7. blood brain barrier
8. Functional area and functional columns
9. Parasympathetic ganglion 
10. Phrenic nerve and vagus

• GROSS

1.  Compartments of lower limb with nerve and blood supply
2. Blood supply of thyroid,oesophagus,ureter,Anal canal 
3. Waldeyer ring
4. External carotid artery
5. Circle of willis
6. Muscle of eye
7. Brachial plexus (Sensory and motor supply of upper limb)
8. Perineum
9. Cruciate ligaments
10. Vocal cords
11. Mediastinum
12. IVC tributaries
13. Cavernous sinus and superior orbital fissure 
14. Splanchanic plexus

2. BIOCHEMISTRY

• Inborn error of metabolism (Types,Enzyme deficient,hallmark feature,Investigation of choice and treatment)
• Rate limiting step 
• Carbohydrate metabolism (Glycolysis,Glycogen storage disease,Glucogenesis,glycogenolysis,PFK-1)
• Lipid metabolism ( Hyperlipoproteinemia and hypolipoproteinemia)
• Vitamin (Coenzyme)
• Electron transport chain inhibitor
• Heme metabolism and Porphyria
• Ketone body formation 
• Urea cycle disorder
• Competitive, non competitive and allosteric inhibitors
• Mitochondrial disorders 
• Amino acid disorder
• Lead poisoning
• Translation process 

3.PHYSIOLOGY

• Receptors
• Neurotransmitter and functions
• Second messenger
• Reflexes
• Baroreceptors and chemorecptors
• JVP 
• ECG And EEG
• Spirometry
• RAAS 
• Counter current exchanger and multiplier
• Factors affecting compliance of lung 
• Action potential
• Smooth muscle and cardiac muscle
• Channels and types 
• GIT hormones 
• Tracts and lesions(brown sequerd syndrome)
• LH,FSH,GH and insulin glucagon

 Following are the list of 2nd year topics.

1.FORENSIC MEDICINE

• Ballistics (Bullet ranges)
• Identification (female male, blood sample)
• Recent amendments in acts (POCSO act, MTP Act)
• Application of IPC,CrPC sections
• Postmortem changes
• Dentition And Xray of wrist elbow and pelvis to determine age
• Injuries -fracture of skull, RTA, Bruise
• Toxicology- Plant based image, Preservation of viscera, Snakes,Arsenic, OP poisoning,Mercury,cadmium,Cardiac poison
• Consent
• Grievous hurt and murder vs culpable homicide
• Seminal stains
• Dowry death and Rape
• Battered baby syndrome
• Plant Toxicology (castor,abrus,strychnine,Dhatura,Aconite,Oleander,Calotropis,Opium,Cannabis)

2. PATHOLOGY-

• Breast cancer, Lung cancer and Ovarian and testicular cancer
• CD markers
• Hemolytic anemia
• Vasculitis
• Endocarditis And MI
• Types of hypersensitivity reaction
• Platelet and coagulation disorder(ITP,TTP,hemophilias,vWD)
• Stains And vacutainers
• Transfusion reaction 
• Graft rejction
• Crohns vs Ulcerative colitis
• Necrosis, apoptosis and its variant
• Mode of inheritance
• Leukemia and lymphoma prognostic markers
• Renal histology and gross
• Liver histology and gross
• CNS tumors 

3.PHARMACOLOGY

• Antimicrobial Drug of choice and mechanism of action 
• Classification - aminoglycoside , MRSA And drugs for cystic fibrosis
• Hypolipidemic Agents 
• Asthma ( New drugs and guidelines)
• Arthritis (RA and gout)
• General pharmacology ( Pharmacokinetics,clinical trial,Pharmacodynamics)
• Concentration dependent kinetics and time dependent kinetics and post antibiotic effect
• Anti TB drugs
• Anti viral and anti HIV (anti hep B and C)
• Anti fungal
• CVS- MI ,HF, angina managment
• Endocrine- DM,Osteoporosis,SERM,SERD,Gnrh agonist
• GIT-Constipation (opioid induced,IBS related) ,Diarrhea,peptic ulcer
• CNS-Anti epileptic, Sedative,lithium toxicity,neurodegenerative disorder, side effect 
• ANS- Emergency medicines,anaphylaxis, receptors ,poisoning 
• Chemotherapy-Anticancer,monoclonal antibody,small molecules,kinase inhibitors
• Prostaglandins 
• Insulin 

4.MICROBIOLOGY-

• Sterilisation and disinfection (Indicator)
• Immunology (Antibody,complement deficiency,Primary immunodeficiency)
• Latest outbreaks (Zika,Congohemorrhagic fever,Ebola,Corona)
• Sexually transmitted infections
• Vectors
• Parasitology -Eggs
• Congenital infections-Toxoplasmosis,congenital syphillis,rubella,herpes,varicella
• HPV infection,HHV-8
• Bioterrorism
• Larva migrans,larva currens (cutaneous and visceral)
• CD4 counts and Opportunistic infection
•  HIV and TB
• Food poisoning
• Atypical bacteria treatment and infection 
• Dimorphic fungi
• Actinomycosis,Botryomycosis and eumycetoma
• Meningitis
• Exanthematous disease
• Neisseria,diphtheria,Listeria,bacillus anthrax,legionella,campylobacter jejuni
• Bacterial virulence factors,growth factors
• Rickettsial disease, spirochetes(weils ds) 
• Drug resistance mechanism

Following is the list of 3rd year topics.

1.COMMUNITY MEDICINE-

• Surveillance programs
• Sensitivity, specificity,PPV and NPV (Screening of disease)
• Types of studies 
• Odds ratio and relative risk ratio
• Bias
• Sampling 
• Biostatistics- central tendency  (Box and whisker plot )
•  Level of prevention 
• Vaccine and types (Toxoid and live attenuated)
• Demography and family planning
• Biomedical waste
• Health programmes ( RNTCP, HIV)
• Communication
• Nutrition and related programmes
• Disaster
• Null hypothesis,P value and alpha value
• Confidence limit 

2.OPHTHALMOLOGY-

•  Refractive errors (Astigmatism)
• Surgery and post op complication(Glaucoma,cataract,squint)
• Conjuctivitis
• Corneal ulcer (Bacterial,fungal and herpetic) (Stains)
• ROP and systemic retinopathy (Hypertensive and diabetic retinopathy)
• Retinitis pigmentosa and syndromes
• Retinal detachment and cause
• Retinoblastoma
•  Strabismus
• Optic neuritis
• Visual field defect 
• Blow out fracture and trauma to eye
• Glaucoma and drugs(Contraindication and indication)
• Managment of ptosis
• Light reflex and accomodation reflex and pupil
• 3,4,6 Cranial nerve
•  OCT ,Fluorescein angiograhy,tonometers,charts,
• Sudden loss of vision and gradual loss of vision differentials

3. ENT-

• Appearance of tympanic membrane in various disease
• Surgery (Tonsillectomy,Adenoidectomy,Mastoidectomy)
• Paranasal sinus
• CSF rhinorrhea
• Laryngeal disease (Papilloma,vocal cord paralysis, laryngeal muscles action, laryngeal cancers)
• Tracheostomy
• Abscess 
• Nasopharyngeal carcinoma
• Juvenile angiofibroma
• Test of hearing and vertigo
• Otosclerosis
• Cochlear implants
• Oral cavity cancers 
• cervical Lymph node  and neck dissections

 Following is the list of Final year topics.

 1.OBSTETRIC AND GYNECOLOGY-

• Pre-eclampsia (Definitions)
• HELLP
• PPH (prophylaxis and treatment)
• Perineal tear (Types and managment)
• Diabetes and anomalies scan 
• Shoulder dystocia maneuvers
• Molar pregnancy (High risk and low risk for GTN)
• Ectopic (Diagnosis, Investigation and managment)
• Abortions 
• Recurrent pregnancy loss (Investigations and causes)
• Cervical incompetence
• MTP
• Diagnosis and physiological changes of pregnancy 
•  Abruptio vs placenta previa vs Vasa previa
• Heart disease
• MgSO4 and drug
• Fetal monitoring -NST,BPP,doppler
• Twins and complications
• Labor-stages,partogram
• Placenta types and associated pathology
• Rh incompatibility
• Amenorrhea (primary and secondary)
• Mullerian anomalies (Class)
• Asherman, AIS,Gonadectomy indication
• Puberty and precocious puberty
• Menopause (Hormone replacement therapy guidelines) 
• Postmenopausal bleeding and premature ovarian failure (Levels of FSH)
• Semen analysis (Evaluation and IUI and TESE)
• PCOS -Diagnosis,drugs
• Endometriosis
• Cervical,vulval,ovarian,endometrial cancer,Fibroid
• Krukenberg
• PID
• Prolapse 
• Emergency contaceptives
• IUD
• Absolute contraindications in whole subject
• Female sterilisation  

2.PEDIATRICS-

• Developmental milestones
• Neonatal reflexes
• Neonatal resuscitation
• Jaudice,sepsis,Hyaline membrane disease
• Congenital infections-TORCH
• Vaccines(IAP and NIS)
• Diarrhea,pneumonia,dehydration managment
• Pediatric epilepsy
• Febrile seizure (Risk factors,recurrent risk,prohylaxis)
• Severe acute malnutrition
• Rickets
• meningitis
• Neuro-Cerebral palsy and neurocutaneous syndrome
• Pediatric vasculitis-HSP and Kawasaki Disease
•  Nephrotic syndrome
• Congenital heart disease( VSD,TOF,TGA and ductus dependent CHD)
• Trisomies
• Hypoxic Ischemic encephalopathy VS Periventricular leukomalacia
• Fluid managment including shock managment in children
• Childhood pneumonia, Epiglottitis, Acute laryngotracheobronchitis
• Microcephaly and macrocephaly 
• Hydrocephalus and Neural tube defect  
• Fetal alcohol syndrome,warfarin syndrome

3. ANESTHESIA-

• IV anesthetic agents (Propofol)
• Day care surgery (Drug of choice)
• Venous air embolism
• Local anesthetic (Remember concentration also)
• Vaporisers color 
• Inhalational agents 
• Monitoring (Capnography)
• Color coding of cylinder
• Circuits
• Mallampati and ASA grading
• Premedication duration of stoppage and continuation
• Muscle relaxant
• Airway devices
• Endotracheal tube (formula)
• Epidural vs spinal anesthesia (Level of blocks)
• Modes of ventilation

 4.DERMATOLOGY-

•  Pigmentation Diseases 

1. Hyperpigmentation
2. Nevus (Nevus of ota/mongolian spot/CMN/AMN)
3. Melasma
4. Acanthosis nigricans
5. Becker nevus
6. Hypopigmentation -PKDL/Pityriasis versicolor/alba/Hansens
7. Depigmentation-Vitiligo/Contact leukoderma

• Signs (Auspitz,nikolsky,bulla spread sign)
• Histopathology of psoriasis and lichen planus
• Mast cell disorder-Urticaria pigmentosa image
• Papulosquamous disease - Psoriasis ,lichen planus
• Treatment of Psoriasis
• STD (Syphillis,chancroid,donovanosis,Herpes genitalis,syndromic approach)
• Microbiology of STD organism( Dark ground,school of fish,Tzanck smear,Donovan body,Gonococcus)
• Drug Reaction -Fixed drug eruption, erythema multiforme,SJS/TEN
•  Blistering disease 

1. Pemphigus(clinical treatment)
2. Bullos pemphigoid
3. dermatitis herpetiformis
4. Histopathology of blister level and Direct immunofluorescence image

• Infections

1. Fungal (Tinea /pityriasis versicolor)
2. Hansens 
3. TB
4. Viral (HPV/HHV/Molluscum contagiosum)

• Hair disease-Alopecia images,DLE,trichotillomania
• Acne,Rosacea
• cutaneous markers of internal malignancy

5.RADIOLOGY-

• Emergency radiology-RTA,splenic injury,FAST,Perforation
• Radiological anatomy especially applied aspect
• CNS tumor
• Bone tumor
• BIRADS
• TIRADS
• Radiation physics and acute radiation syndrome
• Radiotherapy basics
• Contrast in various studies
• USG and doppler
• Doppler waveforms

6.ORTHOPEDICS-

• Knee joint (Everything)
• Shoulder dislocation
• Bone (Oncology+radiological picture)
• Pediatric Hip(Rdaiology +managment)
• Infections(TB,Osteomyelitis)
• CTEV
• AVN
• Tennis elbow and dequeverian
• Eponyms and test
• Blood supply of femur
• Pseudoarthrosis
• Genu varum/valgus,cubitus varus/valgus
• malunion 
• Instruments

7.SURGERY-

• Glasgow coma scale (Changes)
• Burn
• Cannula color coding 
• Triage
• Trauma
• Incisions,suture,foleys,NG tube,Knots,Scores
• Latest updates in breast cancer,thyroid and hepatobiliary cancers,Pancreatic cancer,stomach,colorectal cancer
• Bed sores staging 
•  Renal stones managment
• Gall stone managment and surgical complication
• Bariatric surgery
• Acute pancreatitis managment 
• Upper GI and lower GI bleed management and causes
• Aortic aneurysm
• Meckel diverticulum
• Wound classification
• Cancer-(Breast,rectum,stomach,oesophagus,HCC,prostate,thyroid)
• Cancer follow up duration 
• Carcinoid and GIST and gastrinoma

 8.MEDICINE-

•  ECG visuals
• Cardiac emergencies-Arrest,Unstable angina,MI,Arrhythmia,Dissection
• Respiratory emergency-Pulmonary embolism,pneumothorax,Asthma 
• Stroke
• Meningitis (Bacterial,viral,aseptic)
• Approach to patient in Coma
• Seizure
• Electrolyte imbalance
• ABG
• Hypertension and its emergency and management
• Murmurs and valvular lesions
• Pericardial d/o
• hepatitis(Viral,autoimmune)
• Non alcoholic and alcoholic liver disease
• Glomerular disease
• UTI
• CKD
• DM (management of different complications)
• Neurodegenerative d/o ,neuropathy,myopathy
• Septic shock guidelines
• GBS
• Poisoning 
• New asthma guidelines
• RTA and Inherited channelopathies
• MEN syndrome
• SIADH, DI,Pheochromocytoma
• AIDS defining illness
• Connective tissue disorder
• Infective endocarditis and rheumatic heart disease
• Prakinson and alzheimers
• IBS,UC ,Crohns
• Cardiomyopathy
• Jones and dukes criteria
• dyslipidemia management 

10.PSYCHIATRY-

• General psychiatry (terms and its meaning )
• MMSE
• Psychotic disorders

1. Schizophrenia
2. Delusional d/o- Named syndromes (Capgras,Fregoli,Othello,Ekbom)

• Mood disorder (Treatment is very important)

1. Mania
2. Depression
3. Bipolar

• Neurotic disorder 

1. Anxiety disorder
2. OCD related disorder
3. Dissociative disorder
4. Trauma and stress related disorder
5. Somatoform disorder

• Substance abuse and deaddiction
• Organic mental disorder(dementia)
• Sleep disorder
• Eating disorder
• Sexual disorder
• Personality types and disorder
• Drugs (SSRI and its sideeffect)
• Psychotherapy types and choice
• Defence mechanism  

You can edit this according to you. 

Hope it will help.

-Upasana Y.

Zika virus mnemonic

High-yield : Risk of stroke with cardioversion

Hello

Electrical/chemical cardioversion performed in a case of atrial fibrillation may carry a high-risk of stroke, especially if >48 hours of time has passed (thrombus formation takes about 48 hours).

Friedreich's Ataxia Mnemonic

Check out this mnemonic if you have difficulty memorizing it :)

Coronary artery dominance and EKG changes

Hello, hello!

Coronary arterial dominance is defined by the vessel which gives rise to the posterior descending artery (PDA).

Diabetic Ketoacidosis in just 5 minutes

Video by Drashtant 

Thioamides in pregnancy

Hello

Propylthiouracil is a pro. It always comes first (used in first trimester of pregnancy).
Methimazole causes Malformations in the embryo (teratogenic).

There are two M's in MethiMazole. This drug is used in second (and third trimester of pregnancy).
Propylthiouracil piles up, causing liver toxicity, thus limiting its use.

Hope it helps
- Jaskunwar Singh

COVID-19: effects on reproduction

Hello

In this post, I will be talking about effects of SARS-CoV-2 on the male reproductive system, as evidenced from a recent study.

COVID-19: Trained immunity from BCG vaccine

Would BCG vaccination really help in immunizing up against SARS-CoV-2?

Let's dig in. 

BCG is a live-attenuated strain derived from an isolate of Mycobacterium bovis used widely across the world as a vaccine for tuberculosis (TB). But that's not all, BCG vaccination is a potential goldmine against so many diseases.