Sunday, October 25, 2015
Drugs causing hemolysis in G6PD deficiency mnemonic
Tips on how to find vein or phlebotomy
Tuesday, October 20, 2015
Study group discussion: Carcinoid syndrome
Sunday, October 18, 2015
Study group discussion: What causes Carharts notch?
In otosclerosis, why carharts notch at 2000 Hz in PTA?
Carhart attributed this phenomenon to "mechanical factors associated with stapedial fixation."
But why the greatest dip at 2 kHz?
The ossicular chain has two basic modes of vibration. The first mode, with a peak around 1200 Hz, is the primary mode for AC stimulation. This mode is associated with a "hinging" motion of the ossicles caused by AC stimulation of the tympanic membrane at the umbo. The second mode, with a peak around 1700 Hz, is described as a "pivoting" motion of the malleus/incus, with an axis of rotation somewhat orthogonal to the axis of rotation associated with the "hinging" motion. The second mode is less robust than the primary mode for AC stimulation, but it is the dominant mode when excited by BC stimulation. A decreased mobility of the ossicular chain at 1700 Hz due to otosclerosis also affects the surrounding frequencies, but is seen most prominently as a BC loss at 2000 Hz in audiometric testing.
Thursday, October 15, 2015
Atypical carcinoid syndrome mnemonic
Carcinoid tumors are neuroendocrine tumors of the GI tract. They can make high levels of neuropeptides and amines, like serotonin, which can cause brief episodes of flushing, diarrhea, cough, wheezing, shortness of breath, heart disease, and in rare cases, pellagra. (Typical carcinoid syndrome)
Atypical carcinoids have a normal plasma serotonin level. They are characterized by extended episodes of deep purple flushing, headache, shortness of breath, and in rare cases, lacrimation (tears).
Wednesday, October 14, 2015
Following Medicowesome
I feel that email is the best option.
You can follow by any RSS feed here.
As for social media, I regularly update Facebook and Twitter.
Twitter: https://twitter.com/medicowesome
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For those of you who use Whatsapp, the Broadcast list is a wonderful idea.
I add contacts to my broadcast list and send links to blog posts (new and old) on a daily basis.
Broadcast list: http://medicowesome.blogspot.in/2015/09/medicowesome-broadcast-list.html
Submissions: Anti-diarrhoeal and drugs used for constipation notes
Tuesday, October 13, 2015
Study group discussion: Pharmacology of drugs used in Parkinsons disease
Bradykinesia is due to deficiency of dopamine.
Rigidity is due to uncompensated increase in acetylcholine.
Why levodopa is always given in combination with carbidopa and entacapone?
Carbidopa is given to protect levodopa against dopa decarboxylase enzyme which causes its peripheral breakdown. Peripheral conversion of dopamine is harmful.. Can cause cardiac arrhythmias and postural hypotension.
Entacapone is given to block COMT.
Difference between entcapone and talcapone?
Study group discussion: Why are platelets low in hepatic disease?
You need cytokines to tell the marrow to synthesis platelets. They are synthesized chiefly by liver.
It is also been associated with the concept of hypersplenism leading to sequestration of thrombocytes in the enlarged spleen.