Hi everyone! What is oxygen - haemoglobin dissociation curve or oxygen binding curve?
The oxygen - haemoglobin dissociation curve plots the proportion of haemoglobin in its saturated form on the vertical axis (fractional saturation of hemoglobin) against the prevailing oxygen tension on the horizontal axis. What does it tell?
It tells you the affinity of hemoglobin for oxygen. How does it do that?
It's simple!
If the curve shifts towards the right, hemoglobin has decreased affinity for oxygen.
If the curve shifts towards the left, hemoglobin has increased affinity for oxygen. How do I remember the shift in curves? Remember: Left shifted curve doesn't want to leave oxygen.
Happy friday everyone!
We’ll learn about obstructive and restrictive lung diseases today.
This is just a short summary for a quick review :)
Obstructive lung diseases - Characterized by airway obstruction.
You have an obstruction in air flow resulting in air trapping in the lungs. Increased compliance: Due to the loss of alveolar and elastic tissue.
You have a problem getting air out of your lungs. Mnemonic: Obstructive Out They breathe like “poof poooooof”
In and oooooout
They take infinity to get it all out =P
So, FEV1 / FVC is decreased.
TLC and RV increased - Flow volume loop shifts towards left.
Examples: Any pathology that decreases the ability to develop a positive intrapleural pressure.
(Airways close prematurely at high lung volumes!)
Chronic bronchitis
Asthma
Bronchiectasis
Emphysema
COPD Restrictive lung diseases - Characterized by restriction of lung expansion.
You have a problem getting air into your lungs. Reduced compliance: Lungs become fibrotic, lose their distensibility and become stiffer. Mnemonic: Restrictive Reduced compliance
They breathe like “poof pof”
In and out
They get everything out in one second =P
So, FEV1 / FVC is increased.
TLC and RV decreased - Flow volume loop shifts towards the right.
Examples: Any pathology that decreases the ability to develop a negative intrapleural pressure.
Pulmonary fibrosis
Asbestosis
Sarcoidosis
Pneumoconioses
Kyphoscoliosis
ARDS
Polio
Obesity That's all!
I know you must've found the "poof" sounds pretty weird because that isn't the way you breathe
But they are a funny and they help me remember so I put it up anyway ^___^"
Just like "lup dubb" are official sounds for heart beats.. Which sounds would you assign to inspiration and expiration?
Hi everyone! What is diastolic blood pressure?
It is the pressure that is exerted on the walls of the various arteries around the body in between heart beats when the heart is relaxed.
It is the minimum pressure in the entire cardiac cycle.
So it basically represents amount of blood in arterial system during diastole.
Hi everyone!
This is my attempt of explaining everything I know about free water clearance.. Hope you understand :)
What is free water clearance?
Free water clearance (CH2O) is the volume of blood plasma that is cleared of solute-free water per unit time.
What does it mean? @_@ Water follows salt everywhere it goes.
[Think of salt and water as a lovey dovey couple, in a very codependent relationship of course, water being the lead role xP ]
Do you know viruses have various shapes?
The simple viruses are either icosahedral or helical.
Cool and important fact: Icosahedral viruses can either be simply a naked caspid virus or it can be an enveloped caspid virus.
But if a virus is helical, it HAS to be enveloped and surrounded by a nice lipid bilayer (mostly derived from the host cell membrane)
How I remember that helical viruses are always enveloped is:
Think of our DNA! We have a helical structure.. So the helical viruses can not survive without our cell membranes. Helical virus forms can not be naked.
I know it's stupid but it makes life easy for me < 3
If you want to stuff your hippocampus with some other facts: